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EMAGE:3926

Gbx2 gastrulation brain homeobox 2 ( MGI:95668)
TS14 (8.5 dpc)
in situ hybridisation

Data Images
EMAGE:3926
Fig5KCopyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.2001.0531] Dev Biol 242: 204-23, Tian E; Kimura C; Takeda N; Aizawa S; Matsuo I, Otx2 is required to respond to signals from anterior neural ridge for forebrain specification. Copyright 2002

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:3926Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
3926_wholemount_strong_3D_1.wlz
3926_wholemount_moderate_3D_1.wlz
3926_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3926_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
future hindbrain
detected detected
regionalExpression in anterior metencephalon.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:20957
Entity Detected:Gbx2, gastrulation brain homeobox 2 ( MGI:95668)
Notes:The Gbx2 probe used in this study by Tian et al., 2002 [PMID:11820816] is indicated as that previously described by Bulfone et al., 1993 [PMID:7687285] i.e. "a Gbx-2 riboprobe was transcribed from a 0.65kb fragment derived from the 3' untranslated region of the Gbx-2 CDNA clone". Editors note: The Gbx2 clone referred to was isolated by M. Frohman and G. Martin.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:8.5 dpc
Theiler Stage:TS14
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Tian E; Kimura C; Takeda N; Aizawa S; Matsuo I, 2002 [PMID:11820816] ,, Indexed by GXD, Spatially Mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1006/dbio.2001.0531] [ PMID:11820816] Tian E, Kimura C, Takeda N, Aizawa S, Matsuo I 200 Otx2 is required to respond to signals from anterior neural ridge for forebrain specification. Dev Biol (242):204-23
 [ PMID:7687285] Bulfone A, Puelles L, Porteus MH, Frohman MA, Martin GR, Rubenstein JL 1993 Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt-3 in the embryonic day 12.5 mouse forebrain defines potential transverse and longitudinal segmental boundaries. J Neurosci (13):3155-72
Links:MGI:2179009 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI