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EMAGE:396

Wnt1 wingless-related MMTV integration site 1 ( MGI:98953)
TS20 (12.5 dpc)
in situ hybridisation

Data Images
EMAGE:396 EMAGE:396
Figure 4K of Wassarman et al., 1997 [PMID:9247335] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright. Figure 4I of Wassarman et al., 1997 [PMID:9247335] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Image K is a darkfield image Image I is the corresponding brightfield image. Image annotations: mb - midbrain; isc - isthmic constriction; cb - cerebellum.
Expression Pattern Description
Spatial Annotation:
EMAGE:396EMAGE:396Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D context movie

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
396_voxel_strong_3D_1.wlz
396_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:396_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
embryo
detected detected
regional
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1331398
Entity Detected:Wnt1, wingless-related MMTV integration site 1 ( MGI:98953)
Notes:The Wnt1 probe used in this study by Wassarman et al., 1997 [PMID:9247335] is described as being that previously published by McMahon et al., 1992 [PMID:1534034] . McMahon et al describe three Wnt1 in situ probes.
Chemistry:RNA
Strand:antisense
Label:S35
Specimen
Organism:mouse
Age:12.5 dpc
Theiler Stage:TS20
Mutations:none (wild-type)
Preparation:section
Procedures
Embedding:cryosection
Staining procedure:autoradiography
General Information
Authors:Wassarman et al., 1997 [PMID:9247335] Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:9247335] Wassarman KM, Lewandoski M, Campbell K, Joyner AL, Rubenstein JL, Martinez S, Martin GR 1997 Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function. Development (124):2923-34
 [ doi:10.1016/0092-8674(92)90222-X] [ PMID:1534034] McMahon AP, Joyner AL, Bradley A, McMahon JA 1992 The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum. Cell (69):581-95
Links:MGI:1331434 same experiment
 EMAGE:831 same embryo
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI