EMAGE mouse gene expression spatial database

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EMAGE:3976

Zic3 zinc finger protein of the cerebellum 3 ( MGI:106676)
TS08 (6.0 dpc)
in situ hybridisation

Data Images


Figure 2B. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2004.03.003] Gene Expr Patterns 4: 505-11, Elms P; Scurry A; Davies J; Willoughby C; Hacker T; Bogani D; Arkell R, Overlapping and distinct expression domains of Zic2 and Zic3 during mouse gastrulation. Copyright 2004.	Figure 2C. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2004.03.003] Gene Expr Patterns 4: 505-11, Elms P; Scurry A; Davies J; Willoughby C; Hacker T; Bogani D; Arkell R, Overlapping and distinct expression domains of Zic2 and Zic3 during mouse gastrulation. Copyright 2004.	Figure 2D. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2004.03.003] Gene Expr Patterns 4: 505-11, Elms P; Scurry A; Davies J; Willoughby C; Hacker T; Bogani D; Arkell R, Overlapping and distinct expression domains of Zic2 and Zic3 during mouse gastrulation. Copyright 2004.	Figure 2E. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2004.03.003] Gene Expr Patterns 4: 505-11, Elms P; Scurry A; Davies J; Willoughby C; Hacker T; Bogani D; Arkell R, Overlapping and distinct expression domains of Zic2 and Zic3 during mouse gastrulation. Copyright 2004.

Expression pattern clarity:
Find spatially similar expression patterns:

Notes:

Note: Proximal-distal level of the sections is shown in Fig2E. Accompanying wholemount spatial annotation (for Fig2E) in EMAGE:3977. This embryo is described as "pre-gastrulation stage".

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

3D mapping

spatial mapping

View mapped 3D expression image

Download individual expression domains:

3976_voxel_notDetected_3D_1.wlz

3976_voxel_strong_3D_1.wlz

3976_voxel_notDetected_3D_2.wlz

3976_voxel_strong_3D_2.wlz

3976_voxel_notDetected_3D_3.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:3976_all_domains.zip

Find spatially similar expression patterns:

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

epiblast

detected

regional

Expression is absent in the most distal epiblast cells.

embryo endoderm

not detected

homogeneous

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	MGI:3526556
Entity Detected:	Zic3, zinc finger protein of the cerebellum 3 ( MGI:106676)
Sequence:	sense strand is shown >MGI:3526556 ATTGAATCCCTTCGGGGACTCAACCCACGCTGCGGCCGCCGCCGCTGCCGCCGCTGCCTTCAAGCTGAGC CCAGCCACCGCTCACGATCTGTCTTCGGGCCAGAGCTCAGCGTTCACACCGCAGGGTTCAGGTTATGCCA ATGCCCTGGGCCACCATCACCACCACCATCACCACCATCACGCCAGCCAGGTGCCCACCTACGCGCGGCG TGCCTCCGCCGCTTTCAACTCCACGCGCGACTTTCTGTTCCGTCAGCGCGGTTCTGGGCTCAGCGAGGCA GCCTCCGGGGGCGGGCAGCACGGGCTTTTCGCTGGCTCGGCGAGCAGTCTTCACGCTCCAGCTGGTATTC CTGAGCCTCCTAGCTACTTGCTCTTTCCTGGGCTTCATGAGCAGGGCGCTGGGCACCCGTCGCCCACAGG GCACGTGGACAACAACCAGGTCCATCTGGGGCTGCGCGGGGAGCTATTTGGCCGTGCAGACCCATACCGC CCCGTGGCTAGCCCGCGCACGGACCCCTACGCGGCCAGTGCGCAGTTCCCTAACTATAGCCCCATGAACA TGAACATGGGCGTGAACGTGGCGGCCCACCACGGGCCGGGCGCCTTCTTCCGTTACATGCG
	nt 646 - nt 1266 of NM_009575.1
Notes:	The Zic3 probe used in this study by Elms et al., 2004 [PMID:15261827] was "a cDNA probe corresponding to bases 646-1266 of mouse Zic3 (Acc No.: NM_009575)".
Chemistry:	RNA
Strand:	antisense

Specimen

Organism:	mouse
Strain:	involves: 101/HeH * C3H/HeH
Age:	6.0 dpc
Theiler Stage:	TS08
Mutations:	none (wild-type)
Preparation:	section

Procedures

Fixation:	4% paraformaldehyde
Embedding:	cryosection

General Information

Authors:	Elms P; Scurry A; Davies J; Willoughby C; Hacker T; Bogani D; Arkell R, 2004 [PMID:15261827] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ doi:10.1016/j.modgep.2004.03.003] [ PMID:15261827] Elms P, Scurry A, Davies J, Willoughby C, Hacker T, Bogani D, Arkell R 2004 Overlapping and distinct expression domains of Zic2 and Zic3 during mouse gastrulation. Gene Expr Patterns (4):505-11
Links:	MGI:3526650 same experiment
	EMAGE:3977 same embryo
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source