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EMAGE:4022

Nppa natriuretic peptide type A ( MGI:97367)
TS14 (9.0-9.5 dpc)
in situ hybridisation

Data Images
EMAGE:4022 EMAGE:4022
Fig1F. Copyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.2000.9753] Dev Biol 223: 266-78, Christoffels VM; Habets PE; Franco D; Campione M; de Jong F; Lamers WH; Bao ZZ; Palmer S; Biben C; Harvey RP; Moorman AF, Chamber formation and morphogenesis in the developing mammalian heart [published erratum appears in Dev Biol 2000 Sep 1;225(1):266] Copyright 2000 Fig1E. Copyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.2000.9753] Dev Biol 223: 266-78, Christoffels VM; Habets PE; Franco D; Campione M; de Jong F; Lamers WH; Bao ZZ; Palmer S; Biben C; Harvey RP; Moorman AF, Chamber formation and morphogenesis in the developing mammalian heart [published erratum appears in Dev Biol 2000 Sep 1;225(1):266] Copyright 2000

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: AVC= atrioventricular canal, IFT= inflow tract, IC= inner curvature, OFT= outflow tract, vIFT= ventral side of IFT, LV= left ventricle, LA= left atrium. Figure 1F is a lateral view; Figure 1E is a frontal view.
Expression Pattern Description
Spatial Annotation:
EMAGE:4022Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4022_wholemount_strong_3D_1.wlz
4022_wholemount_moderate_3D_1.wlz
4022_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4022_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
primitive ventricle
detected detected
regionalExpression is stronger in the left ventricle and weaker in the right ventricle.
common atrial chamber
detected detected
regionalExpression is in the primordia of the atrial appendages.
bulbus cordis rostral half
detected detected
regionalExpression is at the laterodorsal side of the posterior pole of the looping heart tube.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1927599
Entity Detected:Nppa, natriuretic peptide type A ( MGI:97367)
Notes:The Nppa (ANF) probe used in this study by Christoffels et al., 2000 [PMID:10882515] is of undefined sequence.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Strain:FVB
Age:9.0-9.5 dpc
Theiler Stage:TS14
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
Staining procedure:alkaline phosphatase + BMpurple
General Information
Authors:Christoffels VM; Habets PE; Franco D; Campione M; de Jong F; Lamers WH; Bao ZZ; Palmer S; Biben C; Harvey RP; Moorman AF, 2000 [PMID:10882515] , Indexed by GXD, Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1006/dbio.2000.9753] [ PMID:10882515] Christoffels VM, Habets PE, Franco D, Campione M, de Jong F, Lamers WH, Bao ZZ, Palmer S, Biben C, Harvey RP, Moorman AF 2000 Chamber formation and morphogenesis in the developing mammalian heart. Dev Biol (223):266-78
Links:MGI:1929929 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI