EMAGE mouse gene expression spatial database

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EMAGE:4026

Zic2 zinc finger protein of the cerebellum 2 ( MGI:106679)
TS08 (pre-streak Downs & Davies)
in situ hybridisation

Data Images


Figure 1B. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2004.03.003] Gene Expr Patterns 4: 505-11, Elms P; Scurry A; Davies J; Willoughby C; Hacker T; Bogani D; Arkell R, Overlapping and distinct expression domains of Zic2 and Zic3 during mouse gastrulation. Copyright 2004.	Figure 1A. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2004.03.003] Gene Expr Patterns 4: 505-11, Elms P; Scurry A; Davies J; Willoughby C; Hacker T; Bogani D; Arkell R, Overlapping and distinct expression domains of Zic2 and Zic3 during mouse gastrulation. Copyright 2004.	Figure 1C. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2004.03.003] Gene Expr Patterns 4: 505-11, Elms P; Scurry A; Davies J; Willoughby C; Hacker T; Bogani D; Arkell R, Overlapping and distinct expression domains of Zic2 and Zic3 during mouse gastrulation. Copyright 2004.

Expression pattern clarity:
Find spatially similar expression patterns:

Notes:

Note: Level of sections B and C are shown in A. The corresponding wholemount annotation for A can be found in EMAGE:4025.

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

3D mapping

spatial mapping

View mapped 3D expression image

Download individual expression domains:

4026_voxel_notDetected_3D_1.wlz

4026_voxel_strong_3D_1.wlz

4026_voxel_notDetected_3D_2.wlz

4026_voxel_strong_3D_2.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:4026_all_domains.zip

Find spatially similar expression patterns:

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

embryo endoderm

not detected

homogeneous

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	MGI:3526555
Entity Detected:	Zic2, zinc finger protein of the cerebellum 2 ( MGI:106679)
Sequence:	sense strand is shown >MGI:3526555 GCCATCGGGGTGGGCAGCTTCGCGCGCCACCACCACCACTCGGCCGCGGCAGCGGCGGCTGCGGCGGCCG AGATGCAGGACCGCGAGCTGAGCCTGGCGGCAGCTCAGAACGGCTTCGTGGACTCGGCCGCGGCGCACAT GGGCGCCTTCAAGCTCAACCCCGGGGCACACGAACTGTCTCCTGGTCAGAGTTCGGCGTTCACGTCGCAA GGTCCGGGTGCTTACCCGGGTTCGGCTGCTGCAGCCGCTGCGGCCGCGGCTCTAGGGCCCCACGCCGCAC ACGTTGGCTCCTATTCGGGGCCTCCCTTTAATTCCACCCGGGACTTCCTGTTCCGCAGCCGGGGCTTCGG GGACTCGGCGCCGGGAGGCGGGCAGCACGGGCTCTTCGGACCCGGCGCCGGCGGCCTTCACCACGCGCAC TCGGACGCGCAGGGCCACCTTCTTTTCCCTGGCCTTCCCCCGGAGCAGCACGGGCCGCACGCCTCGCAGA ACGTGCTCAATGGGCAAATGCGCCTAGGGCTGCCGGGCGAGGTGTTCGGGCGCTCGGAGCAATACCGCCA AGTGGCCAGCCCGCGGACCGACCCCTACTCGGCGGCGCAGCTCCACAACCAGTACGGCCCTATGAATATG AACATGGGGATGAACATGGCAGCGGCCGCAGCCCACCACCACCATCACCACCACCACCCTGGTGCCTTTT TCCGCTACATGCGGCAGCAGTGCATCAAGCAAGAGCTC
	nt 273 - nt 1010 of NM_009574.1
Notes:	The Zic2 probe template used in this study by Elms et al., 2004 [PMID:15261827] is indicated as that originally described in Elms et al., 2003 [PMID:14651926] i.e. a "cDNA probe corresponding to bases 273-1010 of mouse Zic2 (accession no. NM_009574) was amplified and cloned into pGEM-Teasy (Promega). An antisense riboprobe was generated to this clone by SalI digest and transcription with T7 polymerase". Editors note: Prior to Dec 24 2003 (which includes when Elms et al first described the template sequence), there was only one version of NM_009574 (NM_009574.1).
Chemistry:	RNA
Strand:	antisense

Specimen

Organism:	mouse
Strain:	involves: 101/HeH * C3H/HeH
Age:	pre-streak Downs & Davies
Theiler Stage:	TS08
Mutations:	none (wild-type)
Preparation:	sectioned wholemount

Procedures

Fixation:	4% paraformaldehyde
Embedding:	cryosection

General Information

Authors:	Elms P; Scurry A; Davies J; Willoughby C; Hacker T; Bogani D; Arkell R, 2004 [PMID:15261827] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ doi:10.1016/j.modgep.2004.03.003] [ PMID:15261827] Elms P, Scurry A, Davies J, Willoughby C, Hacker T, Bogani D, Arkell R 2004 Overlapping and distinct expression domains of Zic2 and Zic3 during mouse gastrulation. Gene Expr Patterns (4):505-11
	[ doi:10.1016/j.ydbio.2003.09.005] [ PMID:14651926] Elms P, Siggers P, Napper D, Greenfield A, Arkell R 2003 Zic2 is required for neural crest formation and hindbrain patterning during mouse development. Dev Biol (264):391-406
Links:	MGI:3526649 same experiment
	EMAGE:4025 same embryo
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source