EMAGE mouse gene expression spatial database

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EMAGE:4054

Tbx10 T-box 10 ( MGI:1261436)
TS15 (9.5 dpc)
in situ hybridisation

Data Images


Figure 3C. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S1567-133X(03)00060-7] Gene Expr Patterns 3: 533-8, Bush JO; Maltby KM; Cho ES; Jiang R, The T-box gene Tbx10 exhibits a uniquely restricted expression pattern during mouse embryogenesis. Copyright 2003.	Figure 3B. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S1567-133X(03)00060-7] Gene Expr Patterns 3: 533-8, Bush JO; Maltby KM; Cho ES; Jiang R, The T-box gene Tbx10 exhibits a uniquely restricted expression pattern during mouse embryogenesis. Copyright 2003.

Expression pattern clarity:
Find spatially similar wholemount expression patterns:

Notes:

Note: ov, otic vesicle; r4, rhombomere 4.

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

wholemount mapping

Download individual expression domains:

4054_wholemount_strong_3D_1.wlz

4054_wholemount_notDetected_3D_1.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:4054_all_domains.zip

Find spatially similar wholemount expression patterns:

EMAGE spatially similar wholemount patterns

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

rhombomere 04

detected

single cell

Expression is in a subset of individual cells in the rhombomere 4 area.

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	MGI:2683115
Entity Detected:	Tbx10, T-box 10 ( MGI:1261436)
Sequence:	sense strand is shown >MGI:2683115 AATCAGAGGCAGTTTGGAGACACCCACCAGAACAGCCCCAAGCTGGGCTTTATGAACATCCAACCAAGTG TCCTGCTCAGGAGGAAAAGCCTCAGCCAGGAAGTCGGACAGAGGACAATCAAGGAGGGAAGTACTGAGAA CTGGGGACGGGTGCATGCTTGAGAGTGAGGTCTGCTGCTGAGCACAGGAGCCGACCCAGTGTCACTCACT GGCGTCCCCTCCCTGGGTAAGGCTGTAGCCTAGCCTGAGCTGAGATCCGGCTGTCCAGCTGTCCGCATGG CAGTCTTCCTGTCTGCTGGCCTTGGGGTACTTGCTCCTCCAGAGACCTGTCCCCATCCCGAGACCAGCAC CAGCTGGGAGTCCCGGCTGGGGACACGATTCCCCTCAGGTTCCTGCACCATGTCTACAGAAGCCCAAGCC ATGGCAGAGCCCACTGGGCAGGGCCCCAAGAACCCACGTGTGTCCAGTGTGATGGTGCAGCTGGAGATGA AGCCACTGTGGGAAGAGTTCAACCAGCTGGGCACAGAGATGATTGTCACCAAAGCGGGCAGGAGGATGTT CCCAACGTTCCAGGTGAAGATCCTGGGCATGGACACGCTGGCTGACTACGCTTTGCTCATGGACTTTATC CCGTTGGATGACAAGAGATACAGGTACGCATTCCACAGTTCTGCCTGGCTGGTGGCAGGCAAGGCAGACC CTGCCACGCCTGGCAGGGTGCACTTCCACCCTGACTCGCCAGCCAAGGGTGCCCAGTGGATGCGGCAGAT TGTGTCCTTTGACAAACTCAAGCTGACCAACAACCTGATGGACGACAATGGCCACATCATCCTCAACTCC ATGCATCGTTATCAGCCCCGTTTCCACGTGGTCTTCGTGGACCCACGCAAGGACAGTGCCCGCTATGCCC AGGAAAACTTCAAGTCCTTTGTCTTCACGGAGACCCAGTTTACAGCTGTGACAGCCTATCAGAACCACAG GATCACGCAGCTGAAAATTGCTAGCAACCCCTTTGCCAAAGGTTTCAGAGAGGCTGACCCAGACTCATGG CCTGTGACCCCCCGGCCACTGCTCAGCATCCCTGCCCGGAGTCGTAGCAGCCTCAGTCCCTGCCTCCTTA AGGGCTCTGCAGAACGAGAGAAAGATACCAGTAAAGCTTCCGCTTCCAGCTCCAGGACCCCTACTCAGCC ACACAATCAGCTGCTGCCTGCCCCTGATGTCCTGCTAGCCCCTGCCACCTACAGACCCCTCCCTTACCAG AACCTGTACCCTGGATCCCCAAGCCGTGCTGGGCCCCCAAGAGCTCGGCTGGCACCTTACCCTCTCCCCA ACATCAGCACGGCTGGAGATCAGGAGGACCCAACCCTCGCAGCTGGGCTGGGACTCCTGCCCACCTCTGC CTTGTGCTTGGTGTCTAATCAAGCCTCGCAGTGATGGCTGAGTGCTGTGGAAGCCCGTTTCCCCTGTGCC CCACCTCTCCTTCCCTCCTCTGTAAGACATCTCCTAAGGCGAGCAGCACAACTGGAAGCTCTACAGCAGT GGGTTCCTGCCTCAAAGTCAGTCTGGGGCCTGCCAGCCTTGGAATCAGGCCTACTTCCTACTCAAAAGCC CTGAATCATGCCCTGCTGCCTCGAGGATGCCTCCTCTAAATCCTGCTTCGAATGTC
	nt 81 - nt 1746 of AY229976.1
Notes:	The Tbx10 probe template used in this study by Bush et al., 2003 [PMID:12915323] was generated by RT-PCR "with total RNA from E11.5 mouse embryos using RT Primer 1 (5'-AATCAGAGGCAGTTTGGAGACACC-3') and RT Primer 2 (5'-GACATTCGAAGCAGGATTTAGAG-3'), which amplified an approximately 1.5 kb product containing the entire Tbx10 open reading frame".
Chemistry:	RNA
Strand:	antisense
Label:	digoxigenin

Specimen

Organism:	mouse
Age:	9.5 dpc
Theiler Stage:	TS15
Mutations:	none (wild-type)
Preparation:	wholemount

Procedures

General Information

Authors:	Bush JO; Maltby KM; Cho ES; Jiang R, 2003 [PMID:12915323] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ doi:10.1016/S1567-133X(03)00060-7] [ PMID:12915323] Bush JO, Maltby KM, Cho ES, Jiang R 2003 The T-box gene Tbx10 exhibits a uniquely restricted expression pattern during mouse embryogenesis. Gene Expr Patterns (3):533-8
Links:	MGI:2683116 same experiment
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source