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EMAGE:4102

Grem1 gremlin 1 ( MGI:1344337)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:4102 EMAGE:4102 EMAGE:4102
Fig6C. Copyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1999.9240] Dev Biol 209: 98-110, Pearce JJ; Penny G; Rossant J, A mouse cerberus/Dan-related gene family. Copyright 1999 Fig6E. Copyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1999.9240] Dev Biol 209: 98-110, Pearce JJ; Penny G; Rossant J, A mouse cerberus/Dan-related gene family. Copyright 1999 Fig6H. Copyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1999.9240] Dev Biol 209: 98-110, Pearce JJ; Penny G; Rossant J, A mouse cerberus/Dan-related gene family. Copyright 1999

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: ldm - lateral dermamyotome; mdm - medial dermamyotome; rp - roof plate.
Expression Pattern Description
Spatial Annotation:
EMAGE:4102Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4102_wholemount_strong_3D_1.wlz
4102_wholemount_moderate_3D_1.wlz
4102_wholemount_possible_3D_1.wlz
4102_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4102_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
trunk somite
detected detected
regionalExpression was seen in the lateral-most aspects of developing somites. An additional domain of expression was seen in the medial aspects of the dermamyotome of maturing anterior somites.
diencephalon roof plate
detected detected
neural tube roof plate
detected detected
future midbrain roof plate
detected detected
regionalExpression was restricted to the roof plate at the midbrain-hindbrain junction area.
future hindbrain
detected detected
regionalExpression was restricted to the roof plate at the midbrain-hindbrain junction area.
forelimb bud mesenchyme
detected detected
regionalExpression was observed in the dorsal and ventral mesenchyme of the emergent limb buds.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1345352
Entity Detected:Grem1, gremlin 1 ( MGI:1344337)
Notes:The Grem1 (Drm) probe used in this study by Pearce et al., 1999 [PMID:10208746] is described as being "made using a 1.2-kb genomic fragment of the mouse Drm locus containing the open reading frame (ORF) and 3' untranslated sequence."
Chemistry:DNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Pearce JJ; Penny G; Rossant J, 1999 [PMID:10208746] , Indexed by GXD, Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1006/dbio.1999.9240] [ PMID:10208746] Pearce JJ, Penny G, Rossant J 1999 A mouse cerberus/Dan-related gene family. Dev Biol (209):98-110
Links:MGI:1345394 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI