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EMAGE:4162

Nkx6-2 NK6 homeobox 2 ( MGI:1352738)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:4162
Figure 2H. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(98)00018-5] Mech Dev 72: 77-88, Qiu M; Shimamura K; Sussel L; Chen S; Rubenstein JL, Control of anteroposterior and dorsoventral domains of Nkx-6.1 gene expression relative to other Nkx genes during vertebrate CNS development. Copyright 1998.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: Arrow indicates posterior limit of expression.
Expression Pattern Description
Spatial Annotation:
EMAGE:4162Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4162_wholemount_strong_3D_1.wlz
4162_wholemount_moderate_3D_1.wlz
4162_wholemount_possible_3D_1.wlz
4162_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4162_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
diencephalon
detected detected
regionalAnterior limit of expression begins near the zona limitans intrathalamica.
future midbrain
detected detected
regionalExpression extends posteriorly along the ventral neural tube.
future hindbrain
detected detected
regionalExpression extends posteriorly along the ventral neural tube.
future spinal cord
not detected not detected
homogeneous
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1206119
Entity Detected:Nkx6-2, NK6 homeobox 2 ( MGI:1352738)
Notes:The Nkx6-2 probe used in this study by Qiu et al., 1998 [PMID:9533954] was 1 kb in length and generated from plasmid pQ444-13.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Qiu M; Shimamura K; Sussel L; Chen S; Rubenstein JL, 1998 [PMID:9533954] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S0925-4773(98)00018-5] [ PMID:9533954] Qiu M, Shimamura K, Sussel L, Chen S, Rubenstein JL 1998 Control of anteroposterior and dorsoventral domains of Nkx-6.1 gene expression relative to other Nkx genes during vertebrate CNS development. Mech Dev (72):77-88
Links:MGI:2450701 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI