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EMAGE:4183

Bmper BMP-binding endothelial regulator ( MGI:1920480)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:4183
Figure 2E. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(03)00113-8] Mech Dev 119 Suppl 1: S179-84, Coffinier C; Ketpura N; Tran U; Geissert D; De Robertis EM, Mouse Crossveinless-2 is the vertebrate homolog of a Drosophila extracellular regulator of BMP signaling. Copyright 2002.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: drg, dorsal root ganglion; fb, forebrain; lb, limb bud; m, mesonephros; np, nasal process; ov, otic vesicle; I and II, first and second branchial arches; arrowhead indicates the neural tube roof.
Expression Pattern Description
Spatial Annotation:
EMAGE:4183Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4183_wholemount_strong_3D_1.wlz
4183_wholemount_moderate_3D_1.wlz
4183_wholemount_possible_3D_1.wlz
4183_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4183_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
genitourinary system
detected detected
regionalExpression is in the mesonephric ridge.
telencephalon
detected detected
dorsal root ganglion
detected detected
nasal process
detected detected
regionalExpression is at the tip of the nasal processes.
1st branchial arch
detected detected
regionalExpression is in the posterior part.
2nd branchial arch
detected detected
otocyst
detected detected
forelimb bud mesenchyme
detected detected
regionalExpression is in the central part.
trunk mesenchyme derived from neural crest
detected detected
regionalExpression is in migrating neural crest cells.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2660968
Entity Detected:Bmper, BMP-binding endothelial regulator ( MGI:1920480)
Sequence:sense strand is shown

>MGI:2660968
AATTCTGCAACCGACCACAGAGAAAACCAGTACCTGAGCTCTGTCAAGGCACAGTGAAGGTGAAGCTTCG
AGCCCATCGAGAATGCCAGAAACTCAAGTCCTGGGAGTTCCAGACCTGCCACTCTACAGTGGACTATACC
ACTTTCTACCGGTCCTGTGTAACAGACATGTGTGAATGTCCAGTCCATAAAAACTGTTACTGTGAGTCAT
TTCTGGCGTATACCCGTGCCTGTCAGAGAGAGGGAATCAAAGTGCACTGGGAACCTCAGCAGAGCTGTGC
AGCCACCCAGTGCAAACATGGTGCTGTGTATGATACCTGTGGCCCAGGATGTGTGAAGACATGTGATAAC
TGGAATGAGATCGGCCCATGCAATAAGCCCTGCATTGCAGGTTGCCACTGCCCAGCAAATCTGGTCCTTC
ATAAGGGAAGGTGCATCAAGCCAGTCCTCTGTCCTCAGCGATGACCTTTGTTCTAGTCCATAGACTTTGA
AATCCAGTGTCTTTGACACTGACATGCAAGAGCCAGTGAAGGACTGTTGTATTTGTGTGCCTGATTCTGC
AAATACACAGAGTATATATGTGTACATATATATAGATATATAGATATATTCGAAACATTTCATCATTTAT
ATAAACTATAGGTGGATTATTATATGTATATTTTTTGCTATAAGACATGTATTATTT
nt 2160 - nt 2846 of NM_028472.1
Notes:The Bmper (crossveinless-2) probe template used in this study by Coffinier et al., 2002 [PMID:14516682] was "a 600 bp EcoRI-XbaI fragment isolated from a partial mouse EST (GenBank BE289531) containing 400 bp of coding sequence and 200 bp of 3' UTR". Editors Note: The start and end co-ordinates of this ~600bp fragment with respect to the mouse Bmper mRNA RefSeq NM_028472.1 were deduced from this information.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Coffinier C; Ketpura N; Tran U; Geissert D; De Robertis EM, 2002 [PMID:14516682] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S0925-4773(03)00113-8] [ PMID:14516682] Coffinier C; Ketpura N; Tran U; Geissert D; De Robertis EM 2002 Mouse Crossveinless-2 is the vertebrate homolog of a Drosophila extracellular regulator of BMP signaling. Mech Dev (119 Suppl 1):S179-84
Links:MGI:2661285 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE