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EMAGE:4196

Dmbx1 diencephalon/mesencephalon homeobox 1 ( MGI:2153518)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:4196
Figure 2I. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(02)00078-3] Mech Dev 114: 219, Broccoli V; Colombo E; Cossu G, Dmbx1 is a paired-box containing gene specifically expressed in the caudal most brain structures. Copyright 2002.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: Dmbx1 is detected in the granule progenitors, which are climbing the rhombic lips to reach the cerebellar anlage (arrows).
Expression Pattern Description
Spatial Annotation:
EMAGE:4196Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4196_wholemount_strong_3D_1.wlz
4196_wholemount_moderate_3D_1.wlz
4196_wholemount_weak_3D_1.wlz
4196_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4196_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
hindbrain
strong strong
regionalExpression is in a bilateral stream of cells in the rhombic lip.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:3039767
Entity Detected:Dmbx1, diencephalon/mesencephalon homeobox 1 ( MGI:2153518)
Sequence:sense strand is shown

>MGI:3039767
CACCAGCAGGCAGCCCAGCAGGCCCAGCACGCCCCCGACTACCGGCCATCAGTGCATGCGCTTACGTTGG
CTGAGCGCCTAGCTGGCTGTACATTTCAAGACATCATCTTGGAGGCCCGCTATGGCTCCCAGCACCGTAA
ACAACGTCGGAGTCGCACGGCGTTCACGGCCCAGCAGCTTGAGGCCCTGGAGAAGACCTTCCAAAAGACT
CATTACCCAGATGTGGTGATGCGCGAGAGGCTGGCCATGTGTACCAATCTTCCTGAGGCCCGTGTACAGG
TGTGGTTTAAGAACCGCAGGGCCAAGTTCCGAAAGAAGCAGCGCAGCCTGCAGAAAGAGCAGCTCCAGAA
ACAGAAGGAGGCCGAGGGTTCCCACGGAGAAGGCAAGGTGGAGGCCCCAGCCTCAGACACGCAGCTGGAA
ACAGAACAGCCTCCTGGTTTGCCCAGTGGTGATCCTCCTGCTGAACTTCAACTGAGCCTGTCGGAGCAGT
CAGCCAGCGAGTCTGCCCCAGAAGATCAGCTGGACCGTGAAGAGGACTCCCGTGCCGAGGAGCCCAAAGC
TGAAAAGAGCCCTGGATCTGAGAGCAAGGTGCCGGGCTGCA
nt 70 - nt 670 of NM_130865.1
Notes:The Dmbx1 probe template used in this study by Broccoli et al., 2002 [PMID:12175515] was described by the authors as "a 600 bp fragment (position 70-670) of mouse Dmbx1". Editor's note: Figure 1B therein shows a sequence for coding region of Dmbx1 (1146nt) and also mentions two other GenBank accession numbers for Dmbx1: NM_130865 and AF421858, all of which (at the date of publication by Broccoli et al) contained sequences 1146nt in length.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Broccoli V; Colombo E; Cossu G, 2002 [PMID:12175515] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S0925-4773(02)00078-3] [ PMID:12175515] Broccoli V, Colombo E, Cossu G 2002 Dmbx1 is a paired-box containing gene specifically expressed in the caudal most brain structures. Mech Dev (114):219-23
Links:MGI:3039779 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE