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EMAGE:4203

Sp8 trans-acting transcription factor 8 ( MGI:2443471)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:4203
Figure 2O. Copyright: This image is from Kawakami Y, Development 2004 Oct;131(19):4763-74 and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: f, forebrain; fl, forelimb; mhb, midbrain/hindbrain boundary.
Expression Pattern Description
Spatial Annotation:
EMAGE:4203Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4203_wholemount_strong_3D_1.wlz
4203_wholemount_moderate_3D_1.wlz
4203_wholemount_weak_3D_1.wlz
4203_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4203_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
future forebrain
detected detected
neural tube
detected detected
future midbrain
detected detected
regionalExpression is at the midbrain/hindbrain boundary.
future hindbrain
detected detected
regionalExpression is at the midbrain/hindbrain boundary.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:3689358
Entity Detected:Sp8, trans-acting transcription factor 8 ( MGI:2443471)
Notes:The Sp8 probe used in this study by Kawakami et al., 2004 [PMID:15358670] contained "1 kb of the 3'UTR". Editors Note: the 3'UTR of Sp8 is 2.7kb in length (see RefSeq NM_177082.3), it is unknown which 1kb of this sequence was used as probe from the published information.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Kawakami Y; Esteban CR; Matsui T; Rodriguez-Leon J; Kato S; Belmonte JC, 2004 [PMID:15358670] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1242/dev.01331] [ PMID:15358670] Kawakami Y, Esteban CR, Matsui T, Rodr�guez-Le�n J, Kato S, Belmonte JC 2004 Sp8 and Sp9, two closely related buttonhead-like transcription factors, regulate Fgf8 expression and limb outgrowth in vertebrate embryos. Development (131):4763-74
Links:MGI:3689360 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI