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EMAGE:4247

Tbx1 T-box 1 ( MGI:98493)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:4247
Fig6A. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.ydbio.2007.02.014] Dev Biol 305: 333-46, Liu Z; Yu S; Manley NR, Gcm2 is required for the differentiation and survival of parathyroid precursor cells in the parathyroid/thymus primordia. Copyright 2007

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: P3 - third pouch; a1 - first arch; a2 - second arch.
Expression Pattern Description
Spatial Annotation:
EMAGE:4247Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4247_wholemount_strong_3D_1.wlz
4247_wholemount_moderate_3D_1.wlz
4247_wholemount_weak_3D_1.wlz
4247_wholemount_possible_3D_1.wlz
4247_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4247_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
3rd branchial pouch dorsal endoderm
detected detected
regionalExpression was detected in the dorsal and anterior domain of the third pouch.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:20612
Entity Detected:Tbx1, T-box 1 ( MGI:98493)
Notes:The Tbx1 probe used in this study by Liu et al., 2007 [PMID:17382312] is indicated as that previously described by Chapman et al., 1996 [PMID:8853987] i.e. "approximately 250 bp of the T-box portion of the cDNA for Tbx1 inserted at the XhoI-ClaI sites of pBluescript II KS(+)". Editors note: There are no XhoI or ClaI sites in the mouse Tbx1 mRNA RefSeq NM_011532.1 - the start and end points of this 250bp probe are unknown from the published description.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Staining procedure:alkaline phosphatase + unspecified
General Information
Authors:Liu Z; Yu S; Manley NR, 2007 [PMID:17382312] , Indexed by GXD, Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/j.ydbio.2007.02.014] [ PMID:17382312] Liu Z, Yu S, Manley NR 2007 Gcm2 is required for the differentiation and survival of parathyroid precursor cells in the parathyroid/thymus primordia. Dev Biol (305):333-46
 [ doi:10.1002/(SICI)1097-0177(199608)206:4<379::AID-AJA4>3.0.CO;2-F] [ PMID:8853987] Chapman DL, Garvey N, Hancock S, Alexiou M, Agulnik SI, Gibson-Brown JJ, Cebra-Thomas J, Bollag RJ, Silver LM, Papaioannou VE 1996 Expression of the T-box family genes, Tbx1-Tbx5, during early mouse development. Dev Dyn (206):379-90
Links:MGI:3722801 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI