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EMAGE:4378

Plxdc2 plexin domain containing 2 ( MGI:1914698)
TS15 (9.5 dpc)
in situ reporter

Data Images
EMAGE:4378 EMAGE:4378
Fig1(top-left). Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2006.12.004] Gene Expr Patterns 7: 635-44, Miller SF; Summerhurst K; Runker AE; Kerjan G; Friedel RH; Chedotal A; Murphy P; Mitchell KJ, Expression of Plxdc2/TEM7R in the developing nervous system of the mouse. Copyright 2007 Fig1(top-right). Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2006.12.004] Gene Expr Patterns 7: 635-44, Miller SF; Summerhurst K; Runker AE; Kerjan G; Friedel RH; Chedotal A; Murphy P; Mitchell KJ, Expression of Plxdc2/TEM7R in the developing nervous system of the mouse. Copyright 2007

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: Arrow - anteromedial region of the telencephalon that includes the choroid plexus epithelium and presumptive cortical hem; arrowhead - floor of midbrain; asterisk - limb-bud; lb - lung bud; MHB - midbrain-hindbrain boundary; s - Plxdc2-betageo expression within the somites.
Expression Pattern Description
Spatial Annotation:
EMAGE:4378Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4378_wholemount_strong_3D_1.wlz
4378_wholemount_moderate_3D_1.wlz
4378_wholemount_weak_3D_1.wlz
4378_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4378_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
limb
detected detected
future midbrain floor plate
detected detected
otocyst
detected detected
lung
detected detected
telencephalon
detected detected
regionalExpression is in an anterior and medial area of the telencephalon that includes the choroid plexus epithelium and presumptive cortical hem.
future midbrain
detected detected
regionalExpression is in the midbrain-hindbrain boundary.
future hindbrain
detected detected
regionalExpression is in the midbrain-hindbrain boundary.
trunk somite
detected detected
regionalExpression is in a segmented pattern.
tail neural plate
detected detected
Expression is in the lateral edges of the neuroepithelium in the region of the still open posterior neuropore.
tail
detected detected
regionalExpression is in the extreme distal tip.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ reporter
Entity Detected:Plxdc2, plexin domain containing 2 ( MGI:1914698)
Notes:Plxdc2 expression was detected in this study by Miller et al., 2007 [PMID:17280871] using a Plxdc2 gene trap mouse line (KST37) described by Leighton et al., [PMID:11242070] as follows: a gene trap vector including a betageo and IRES-PLAP was inserted into intron 3. X-gal staining detected expression in embryos.
Labelled with:B-geo
Specimen
Organism:mouse
Strain:involves: 129P2/OlaHsd
Age:9.5 dpc
Theiler Stage:TS15
Mutations:Plxdc2Gt(pGT1TM)631Wcs/Plxdc2+
Preparation:wholemount
Procedures
Fixation:0.2% glutaraldehyde with a post-fix in 4% paraformaldehyde.
General Information
Authors:Miller SF; Summerhurst K; Runker AE; Kerjan G; Friedel RH; Chedotal A; Murphy P; Mitchell KJ, 2007 [PMID:17280871] , Indexed by GXD, Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/j.modgep.2006.12.002] [ PMID:17280871] Miller SF, Summerhurst K, Runker AE, Kerjan G, Friedel RH, Chedotal A, Murphy P, Mitchell KJ 2007 Expression of Plxdc2/TEM7R in the developing nervous system of the mouse. Gene Expr Patterns (7):635-44
 [ doi:10.1038/35065539] [ PMID:11242070] Leighton PA, Mitchell KJ, Goodrich LV, Lu X, Pinson K, Scherz P, Skarnes WC, Tessier-Lavigne M 2001 Defining brain wiring patterns and mechanisms through gene trapping in mice. Nature (410):174-9
Links:MGI:3707079 allele description
 MGI:3710129 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI