EMAGE mouse gene expression spatial database

Quicksearch Help

(Click the icon to keep this page displayed.)

EMAGE:4393

Lrrtm1 leucine rich repeat transmembrane neuronal 1 ( MGI:2389173)
TS17 (10.0 dpc)
in situ hybridisation

Data Images


Fig1J. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2006.05.004] Gene Expr Patterns 7: 23-9, Haines BP; Rigby PW, Developmentally regulated expression of the LRRTM gene family during mid-gestation mouse embryogenesis. Copyright 2007	Fig1K. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2006.05.004] Gene Expr Patterns 7: 23-9, Haines BP; Rigby PW, Developmentally regulated expression of the LRRTM gene family during mid-gestation mouse embryogenesis. Copyright 2007	Fig1L. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2006.05.004] Gene Expr Patterns 7: 23-9, Haines BP; Rigby PW, Developmentally regulated expression of the LRRTM gene family during mid-gestation mouse embryogenesis. Copyright 2007	Fig1M. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2006.05.004] Gene Expr Patterns 7: 23-9, Haines BP; Rigby PW, Developmentally regulated expression of the LRRTM gene family during mid-gestation mouse embryogenesis. Copyright 2007	Fig1N. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2006.05.004] Gene Expr Patterns 7: 23-9, Haines BP; Rigby PW, Developmentally regulated expression of the LRRTM gene family during mid-gestation mouse embryogenesis. Copyright 2007

Fig1O. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2006.05.004] Gene Expr Patterns 7: 23-9, Haines BP; Rigby PW, Developmentally regulated expression of the LRRTM gene family during mid-gestation mouse embryogenesis. Copyright 2007	Fig1P. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2006.05.004] Gene Expr Patterns 7: 23-9, Haines BP; Rigby PW, Developmentally regulated expression of the LRRTM gene family during mid-gestation mouse embryogenesis. Copyright 2007

Expression pattern clarity:
Find spatially similar wholemount expression patterns:

Notes:

Image annotations: arrowhead - sharp boundary (of expression) present in the midbrain; aer - apical ectodermal ridge; nt - neural tube; ov - otic vesicle; fp - floor plate; asterisk - non-specific signal in otic vesicle. Fig1K is a view from above. Fig1L is a higher magnification of the otic vesicle showing staining in the endolymphatic appendage masked by the non-specific signal in Fig1J (asterisk). Figs1M,O,P are sectons taken from the approximate regions indicated by white lines in Fig1J and 1L.

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

wholemount mapping

Download individual expression domains:

4393_wholemount_strong_3D_1.wlz

4393_wholemount_moderate_3D_1.wlz

4393_wholemount_weak_3D_1.wlz

4393_wholemount_possible_3D_1.wlz

4393_wholemount_notDetected_3D_1.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:4393_all_domains.zip

Find spatially similar wholemount expression patterns:

EMAGE spatially similar wholemount patterns

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

forelimb bud apical ectodermal ridge

detected

hindlimb bud apical ectodermal ridge

detected

forebrain

detected

midbrain

detected

endolymphatic appendage

detected

Expression is in the endolymphatic diverticular appendage of the otic vesicle

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	MGI:3694266
Entity Detected:	Lrrtm1, leucine rich repeat transmembrane neuronal 1 ( MGI:2389173)
Sequence:	sense strand is shown >MGI:3694266 CTGCAGCCCCGGAGCGCAGCAGCAAAGTGAGACATTGTGCGTCTGCCAGATCCTCGGGCCGCGGAGCAGG GCTGCCTCGGGAAACACAGAGGGGTCTTCTCTCGCCCTGCATATAATTAGCCTACACACAAAGGGAGCAG CTGAATGGAGGTTGTCACTCGCTGGAAAAGGATTTCTGACCCAGCGCTTCCAATGGACATTCTCCAGTCT CTCTGGAAAGATTCTCGCTAATGGATTTCCTGCTACTCGGCCTCTGTCTACACTGGCTGCTGAGGAGGCC CTCGGGGGTGGTCTTGTGTCTGCTGGGGGCCTGCTTTCAGATGCTGCCCGCCGCCCCCAGCGGATGCCCG GGGCAGTGTCGGTGCGAGGGGCGGCTGCTGTACTGCGAGGCGCTCAACCTAACCGAGGCGCCCCATAACC TGTCCGGCCTGCTGGGCTTGTCTTTGCGCTACAACAGCCTCTCGGAGCTGCGCGCCGGCCAGTTCACAGG GTTAATGCAGCTCACGTGGCTGTATTTGGATCACAATCACATCTGCTCGGTGCAGGGGGACGCCTTTCAG AAACTGCGCCGAGTTAAGGAACTCACGCTGAGTTCCAACCAGATCACTGAACTGGCCAACACCACCTTCC GGCCCATGCCCAACCTGCGCAGCGTGGACCTGTCCTATAACAAGCTGCAG
	nt 218 - nt 897 of BC027803.1
Notes:	The Lrrtm1 probe used in this study by Haines & Rigby, 2007 [PMID:16860615] is described as follows: "A LRRTM1 cDNA was obtained from IMAGE clone 5321979 digested with PstI. The fragment from 218 to 897 base pairs was cloned into PstI digested pBluescript II KS. An antisense probe was generated by digesting with BamHI and transcribing with T3 polymerase (Roche)."
Chemistry:	RNA
Strand:	antisense
Label:	digoxigenin

Specimen

Organism:	mouse
Age:	10.0 dpc
Theiler Stage:	TS17
Mutations:	none (wild-type)
Preparation:	wholemount

Procedures

Staining procedure:

alkaline phosphatase + NBT/Red Phos

General Information

Authors:	Haines BP & Rigby PW, 2007 [PMID:16860615] , Indexed by GXD, Spatially Mapped by EMAGE.
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ doi:10.1016/j.modgep.2006.05.004] [ PMID:16860615] Haines BP, Rigby PW 2007 Developmentally regulated expression of the LRRTM gene family during mid-gestation mouse embryogenesis. Gene Expr Patterns (7):23-9
Links:	MGI:3694270 same experiment
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source