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EMAGE:448

Nkx2-1 NK2 homeobox 1 ( MGI:108067)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:448 EMAGE:448
Figure 3E of Zoltewicz et al., 1999 [PMID:10529425] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright. Figure 3F of Zoltewicz et al., 1999 [PMID:10529425] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: blue arrowhead(s) - ventral diencephalon; red arrowhead(s) - ventral telencephalon.
Expression Pattern Description
Spatial Annotation:
EMAGE:448Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
448_wholemount_strong_3D_1.wlz
448_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:448_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
diencephalon
detected detected
regionalExpression is present in the ventral region of the anterior diencephalon.
telencephalon
detected detected
regionalExpression is present in the ventral telencephalon.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1346399
Entity Detected:Nkx2-1, NK2 homeobox 1 ( MGI:108067)
Notes:The Titf1 (Nkx2.1) probe used in this study by Zoltewicz et al., 1999 [PMID:10529425] was a gift from John Rubenstein and is of undefined sequence.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Staining procedure:alkaline phosphatase
General Information
Authors:Zoltewicz et al., 1999 [PMID:10529425] Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:10529425] Zoltewicz JS, Plummer NW, Lin MI, Peterson AS 1999 oto is a homeotic locus with a role in anteroposterior development that is partially redundant with Lim1. Development (126):5085-95
Links:MGI:1346416 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI