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EMAGE:4481

Sox3 SRY-box containing gene 3 ( MGI:98365)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:4481
Fig2I. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.ydbio.2006.05.002] Dev Biol 297: 141-157, Jukkola T; Lahti L; Naserke T; Wurst W; Partanen J, FGF regulated gene-expression and neuronal differentiation in the developing midbrain-hindbrain region. Copyright 2007

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: The MHB (midbrain - hindbrain boundary) is marked with a white arrowhead.
Expression Pattern Description
Spatial Annotation:
EMAGE:4481Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4481_wholemount_moderate_3D_1.wlz
4481_wholemount_notDetected_3D_1.wlz
4481_wholemount_strong_3D_1.wlz
4481_wholemount_possible_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4481_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
central nervous system
detected detected
regionalSox3 expression was detected broadly in the CNS, but Sox3-positive cells were not seen in the narrow population of cells between mid- and hindbrain.
rhombomere 01
detected detected
regionalSox3-positive cells were not seen in the narrow population of cells between mid- and hindbrain.
midbrain
detected detected
regionalSox3-positive cells were not seen in the narrow population of cells between mid- and hindbrain.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Sox3 probeA
Entity Detected:Sox3, SRY-box containing gene 3 ( MGI:98365)
Sequence:sense strand is shown

>Sox3 probeA
ATTCGGCACGTGGGGGACCGTTGCCTTGTACCGAAGATGAGGAGGACCGAAAGTTTGGCCGTAACTGTCG
GGGTTTTGTACAAAAGCGAGAAGTCCCGAGCAGCGGAAATGGGACTTGCTAGAGCGCTGGTTCTGACCAC
TGCCCCTCCCTCCCCCTCTGGCTGGGAATCGCTGTGGTGTTTGCGGAGAAACCGCGGCCCCTTCCTCTTC
CCGGATTCCTAGGTTCTTCTGTTGCAGTTGAAAATGTCTTGTTAGTTTGCTATTAATCGAGAACTGAGTG
AGGTTGCCCGCCCCCAAGAACTGCAATGCCTCCACCCCCAGTCGTATTGCTTCTGTTTTCCTCTGGCTTT
TTTTTGGGGGGGGGG
Notes:The Sox3 probe used in this study by Jukkola et al., 2006 [PMID:16782087] was synthesized from the insert of IMAGE:368804.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Jukkola T; Lahti L; Naserke T; Wurst W; Partanen J, 2006 [PMID:16782087] , Indexed and Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:screen
References:[ doi:10.1016/j.ydbio.2006.05.002] [ PMID:16782087] Jukkola T, Lahti L, Naserke T, Wurst W, Partanen J 2006 FGF regulated gene-expression and neuronal differentiation in the developing midbrain-hindbrain region. Dev Biol (297):141-57
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE