EMAGE mouse gene expression spatial database

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EMAGE:4503

Klf4 Kruppel-like factor 4 (gut) ( MGI:1342287)
TS17 (10.5 dpc)
in situ hybridisation

Data Images


Fig2b. Copyright: This image is from [doi:10.1002/ar.a.10089] Ehlermann J; Pfisterer P; Schorle H, "Dynamic expression of Kruppel-like factor 4 (Klf4), a target of transcription factor AP-2alpha during murine mid-embryogenesis." Anat Rec A Discov Mol Cell Evol Biol 2003 273(2):677-80. Reprinted with permission of Wiley-Liss Inc. [PMID:12845703]

Expression pattern clarity:
Find spatially similar wholemount expression patterns:

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

wholemount mapping

Download individual expression domains:

4503_wholemount_possible.wlz

4503_wholemount_notDetected.wlz

4503_wholemount_strong.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:4503_all_domains.zip

Find spatially similar wholemount expression patterns:

EMAGE spatially similar wholemount patterns

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

trunk mesenchyme

detected

regional

Detected in mesenchyme surrounding the fourth arch artery

1st branchial arch

detected

regional

Detected in the medial part of the first branchial arch

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	Klf4 probeA
Entity Detected:	Klf4, Kruppel-like factor 4 (gut) ( MGI:1342287)
Sequence:	sense strand is shown >Klf4 probeA GTGGCCGCGACAACGGTGGGGGACACTGCTGAGTCCAAGAGCGTGCAGCCTGGCCATCGGACCTACTTAT CTGCCTTGCTGATTGTCTATTTTTATAAGAGTTTACAACTTTTCTAAGAATTTTTGTATACAAAGGAACT TTTTTAAAGACATCGCCGGTTTATATTGAATCCAAAGAAGGATCTCGGGCAATCTGGGGGTTTTGGTTTG AGGTTTTGTTTCTAAAGTTTTTAATCTTCGTTGACTTTGGGGCTCGGGTACCCCTCTCTCTTCTTCGGAC TCCGGAGGACCTTCTGGGCCCCCACATTAATGAGGCAGCCACCTGGCGAGTCTGACATGGCTGTCAGCGA CGCTCTGCTCCCGTCCTTCTCCACGTTCGCGTCCGGCCCGGCGGGAAGGGAGAAGACACTGCGTCCAGCA GGTGCCCCGACTAACCGTTGGCGTGAGGAACTCTCTCACATGAAGCGACTTCCCCCACTTCCCGGCCGCC CCTACGACCTGGCGGCGACGGTGGCCACAGACCTGGAGAGTGGCGGAGCTGGTGCAGCTTGCAGCAGTAA CAACCCGGCCCTCCTAGCCCGGAGGGAGACCGAGGAGTTCAACGACCTCCTGGACCTAGACTTTATCCTT TCCAACTCGCTAACCCACCAGGAATCGGTGGCCGCCACCGTGACCACCTCGGCGTCAGCTTCATCCTCGT CTTCCCCAGCGAGCAGCGGCCCTGCCAGCGCGCCCTCCACCTGCAGCTTCAGCTATCCGATCCGGGCCGG GGGTGACCCGGGCGTGGCTGCCAGCAACACAGGTGGAGGGCTCCTCTACAGCCGAGAATCTGCGCCACCT CCCACGGCCCCCTTCAACCTGGCGGACATCAATGACGTGAGCCCCTCGGGCGGCTTCGTGGCTGAGCTCC TGCGGCCGGAGTTGGACCCAGTATACATTCCGCCACAGCAGCCTCAGCCGCCAGGTGGCGGGCTGATGGG CAAGTTTGTGCTGAAGGCGTCTCTGACCACCCCTGGCAGCGAGTACAGCAGCCCTTCGGTCATCAGTGTT AGCAAAGGAAGCCCAGACGGCAGCCACCCCGTGGTAGTGGCGCCCTACAGCGGTGGCCCGCCGCGCATGT GCCCCAAGATTAAGCAAGAGGCGGTCCCGTCCTGCACGGTCAGCCGGTCCCTAGAGGCCCATTTGAGCGC TGGACCCCAGCTCAGCAACGGCCACCGGCCCAACACACACGACTTCCCCCTGGGGCGGCAGCTCCCCACC AGGACTACCCCTACACTGAGTCCCGAGGAACTGCTGAACAGCAGGGACTGTCACCCTGGCCTGCCTCTTC CCCCAGGATTCCATCCCCATCCGGGGCCCAACTACCCTCCTTTCCTGCCAGACCAGATGCAGTCACAAGT CCCCTCTCTCCATTATCAAGAGCTCATGCCACCGGGTTCCTGCCTGCCAGAGGAGCCCAAGCCAAAGAGG GGAAGAAGGTCGTGGCCCCGGAAAAGAACAGCCACCCACACTTGTGACTATGCAGGCTGTGGCAAAACCT ATACCAAGAGTTCTCATCTCAAGGCACACCTGCGAACTCACACAGGCGAGAAACCTTACCACTGTGACTG GGACGGCTGTGGGTGGAAATTCGCCCGCTCGGATGAACTGACCAGGCACTACCGCAAACACACAGGGCAC CGGCCCTTTCAGTGCCAGAAGTGCGACAGGGCCTTTTCCAGGTCGGACCACCTTGCCTTACACATGAAGA GGCACTTTTAAATCCCACGTAGTGGATGTGACCCACACTGCCAGGAGAGAGAGTTCAGTATTTTTTTTTC TAACCTTTCACACTGTCTTCCCACGAGGGGAGGAGCCCAGCTGGCAAGCGCTACAATCATGGTCAAGTTC CCAGCAAGTCAGCTTGTGAATGGATAATCAGGAGAAAGGAAGAGTCCAAGAGACAAAACAGAAATAC
	nt 2 - nt 1958 of U20344.1
Notes:	The Klf4 probe used in this study by Ehlermann et al 2003 [PMID:12845703] was transcribed from "a 1.9 kb fragment of the murine cDNA (Genbank accession number U20344) spanning bases 2-1958 was cloned from an E10.5 cDNA library (Invitrogen, Heidelberg, Germany) and ligated in the EcoRI site of pBS II (KS) as previously described (Pfisterer et al., 2002 [PMID:11741941] ).
Chemistry:	RNA
Strand:	antisense

Specimen

Organism:	mouse
Age:	10.5 dpc
Theiler Stage:	TS17
Mutations:	none (wild-type)
Preparation:	wholemount

Procedures

General Information

Authors:	Ehlermann J; Pfisterer P; Schorle H, 2003 [PMID:12845703] . Indexed and spatially mapped by EMAGE
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ doi:10.1002/ar.a.10089] [ PMID:12845703] Ehlermann J, Pfisterer P, Schorle H 2003 Dynamic expression of Kruppel-like factor 4 (Klf4), a target of transcription factor AP-2alpha during murine mid-embryogenesis. Anat Rec A Discov Mol Cell Evol Biol (273):677-80
	[ doi:10.1074/jbc.M108578200] [ PMID:11741941] Pfisterer P, Ehlermann J, Hegen M, Schorle H 2002 A subtractive gene expression screen suggests a role of transcription factor AP-2 alpha in control of proliferation and differentiation. J Biol Chem (277):6637-44
Links:	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source