Quicksearch Help

(Click the icon to keep this page displayed.)

EMAGE:4509

Lama5 laminin, alpha 5 ( MGI:105382)
TS14 (22 Somite no.)
in situ hybridisation

Data Images
EMAGE:4509
Fig2F. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.ydbio.2005.10.031] Coles et al, 2006. Abnormalities in neural crest cell migration in laminin alpha5 mutant mice. Dev Biol 289:218-28. Copyright 2006.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:4509Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4509_wholemount_moderate_3D_1.wlz
4509_wholemount_possible_3D_1.wlz
4509_wholemount_notDetected_3D_1.wlz
4509_wholemount_strong_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4509_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
branchial arch
detected detected
laminin alpha5 transcripts are detected in branchial arches but have been down-regulated in all other cranial regions.
embryo
detected detected
regionalExpression is detected in the posterior of the embryo, a region where neural crest cells have yet to commence migration.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Lama5 probeA
Entity Detected:Lama5, laminin, alpha 5 ( MGI:105382)
Notes:The Lama5 probe used in this study by Coles et al, 2006 [PMID:16316641] is described as a 392bp fragment of mouse Lama5.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:22 Somite no.
Theiler Stage:TS14
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Coles EG; Gammill LS; Miner JH; Bronner-Fraser M, 2006 [PMID:16316641] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/j.ydbio.2005.10.031] [ PMID:16316641] Coles EG, Gammill LS, Miner JH, Bronner-Fraser M 2006 Abnormalities in neural crest cell migration in laminin alpha5 mutant mice. Dev Biol (289):218-28
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE