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EMAGE:4510

Lats1 large tumor suppressor ( MGI:1333883)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:4510
Fig1G. [doi:10.1038/sj.emboj.7600371] McPherson et al, 2004. EMBO J. 23:3677-88. Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity. © Nature Publishing Group. Reproduced with permission from EMBO J.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotation: arrowhead - expression in mesencephalon.
Expression Pattern Description
Spatial Annotation:
EMAGE:4510Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4510_wholemount__moderate.wlz
4510_wholemount__weak.wlz
4510_wholemount__possible.wlz
4510_wholemount__notDetected.wlz
4510_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4510_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
midbrain
strong strong
Prominent expression detected in mesencephalon
otocyst
strong strong
Prominent expression detected in otic vesicle
embryo ectoderm
strong strong
Prominent expression of Lats1 is found in tissues of ectodermal origin
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Lats1 probeA
Entity Detected:Lats1, large tumor suppressor ( MGI:1333883)
Notes:The Lats1 probe used in this study by McPherson et al., [PMID:15343267] is of unreported identity.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:McPherson JP; Tamblyn L; Elia A; Migon E; Shehabeldin A; Matysiak-Zablocki E; Lemmers B; Salmena L; Hakem A; Fish J; Kassam F; Squire J; Bruneau BG; Hande MP; Hakem R. 2004. [PMID:15343267] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1038/sj.emboj.7600371] [ PMID:15343267] McPherson JP, Tamblyn L, Elia A, Migon E, Shehabeldin A, Matysiak-Zablocki E, Lemmers B, Salmena L, Hakem A, Fish J, Kassam F, Squire J, Bruneau BG, Hande MP, Hakem R 2004 Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity. EMBO J (23):3677-88
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE