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EMAGE:4560

Mnx1 motor neuron and pancreas homeobox 1 ( MGI:109160)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:4560
Fig1C. Copyright: Reprinted with permission from Cell Press from [doi:10.1016/S0896-6273(01)80027-1] Neuron 23: 675-687, Thaler J; Harrison K; Sharma K; Lettieri K; Kehrl J; Pfaff SL, Active suppression of interneuron programs within developing motor neurons revealed by analysis of homeodomain factor HB9. Copyright 1999

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: r5 - rhombomere5; r8 - rhombomere8; OV - otic vesicle.
Expression Pattern Description
Spatial Annotation:
EMAGE:4560Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4560_wholemount_moderate.wlz
4560_wholemount_possible.wlz
4560_wholemount_notDetected.wlz
4560_wholemount_strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4560_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
rhombomere 05
detected detected
regionalA small group of cells in r5, just above the otic vesicle, expresses Hb9/Mnx1
rhombomere 08
detected detected
regionalHb9/Mnx1 RNA is detected in a stripe of MNs (motor neurons) extending from r8 to the tail.
neural tube
detected detected
regionalHb9/Mnx1 RNA is detected in a stripe of MNs (motor neurons) extending from r8 to the tail.
tail neural tube
detected detected
regionalHb9/Mnx1 RNA is detected in a stripe of MNs (motor neurons) extending from r8 to the tail.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Mnx1 probeA
Entity Detected:Mnx1, motor neuron and pancreas homeobox 1 ( MGI:109160)
Notes:The sequence of the Mnx1 (HB9) probe used in this study by Thaler et al., 1999 [PMID:10482235] is not described by the authors.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Thaler J; Harrison K; Sharma K; Lettieri K; Kehrl J; Pfaff SL., 1999 [PMID:10482235] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S0896-6273(01)80027-1] [ PMID:10482235] Thaler J, Harrison K, Sharma K, Lettieri K, Kehrl J, Pfaff SL 1999 Active suppression of interneuron programs within developing motor neurons revealed by analysis of homeodomain factor HB9. Neuron (23):675-87
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE