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EMAGE:4600

Fgfr1 fibroblast growth factor receptor 1 ( MGI:95522)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:4600
Figure 5M. Copyright: This image is from Koizumi Ki, Development 2001 Apr;128(8):1391-402, [PMID:11262239] and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:4600Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4600_wholemount_moderate.wlz
4600_wholemount_notDetected.wlz
4600_wholemount_strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4600_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
trunk paraxial mesenchyme
detected detected
tail paraxial mesenchyme
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:3767619
Entity Detected:Fgfr1, fibroblast growth factor receptor 1 ( MGI:95522)
Notes:The Fgfr1 probe used in this study by Koizumi et al., 2001 [PMID:11262239] is indicated as that originally described by Yamaguchi et al., 1992 [PMID:1321062] i.e. "a partial cDNA representing nt 862 (~43 nt 5' of the transmembrane domain) to nt 2917 (~66 nt upstream of the end of the 3' untranslated sequence) of the previously described mouse basic FGFR (Mansukhani et al., 1990 [PMID:2161540] ). This clone included the entire catalytic kinase domain. A smaller 1-kb probe consisting predominantly of the 3' untranslated region was generated by cutting the partial cDNA with BglII at nt 1851. Both probes revealed identical patterns of expression." Editors note: it is not specified which of these probes was used here.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Koizumi Ki; Nakajima M; Yuasa S; Saga Y; Sakai T; Kuriyama T; Shirasawa T; Koseki H, 2001 [PMID:11262239] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:11262239] Koizumi K, Nakajima M, Yuasa S, Saga Y, Sakai T, Kuriyama T, Shirasawa T, Koseki H 2001 The role of presenilin 1 during somite segmentation. Development (128):1391-402
 [ doi:10.1016/0012-1606(92)90157-C] [ PMID:1321062] Yamaguchi TP, Conlon RA, Rossant J 1992 Expression of the fibroblast growth factor receptor FGFR-1/flg during gastrulation and segmentation in the mouse embryo. Dev Biol (152):75-88
 [ doi:10.1073/pnas.87.11.4378] [ PMID:2161540] Mansukhani A, Moscatelli D, Talarico D, Levytska V, Basilico C 1990 A murine fibroblast growth factor (FGF) receptor expressed in CHO cells is activated by basic FGF and Kaposi FGF. Proc Natl Acad Sci U S A (87):4378-82
Links:MGI:1932859 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI