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EMAGE:4618

Spry2 sprouty homolog 2 (Drosophila) ( MGI:1345138)
TS15 (9.75 dpc)
in situ hybridisation

Data Images
EMAGE:4618
Figure 2N. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(02)00018-7] Mech Dev 113: 163-8, Lin W; Furthauer M; Thisse B; Thisse C; Jing N; Ang SL, Cloning of the mouse Sef gene and comparative analysis of its expression with Fgf8 and Spry2 during embryogenesis. Copyright 2002

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: asterisk denotes branchial arches.
Expression Pattern Description
Spatial Annotation:
EMAGE:4618Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4618_wholemount_moderate_3D_1.wlz
4618_wholemount_weak_3D_1.wlz
4618_wholemount_possible_3D_1.wlz
4618_wholemount_notDetected_3D_1.wlz
4618_wholemount_strong_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4618_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
limb
detected detected
trunk somite
detected detected
future forebrain
detected detected
future midbrain
detected detected
regionalExpression spans the isthmus, the posterior midbrain and anterior hindbrain.
future hindbrain
detected detected
regionalExpression spans the isthmus, the posterior midbrain and anterior hindbrain.
tail
detected detected
telencephalon
detected detected
regionalExpression is in the commissural plate.
1st branchial pouch
detected detected
regionalExpression is in the extreme lateral region.
2nd branchial pouch
detected detected
regionalExpression is in the extreme lateral region.
3rd branchial pouch
detected detected
regionalExpression is in the extreme lateral region.
1st branchial groove ectoderm
detected detected
1st branchial arch mandibular component mesenchyme
detected detected
1st branchial arch maxillary component mesenchyme
detected detected
2nd branchial groove ectoderm
detected detected
2nd branchial arch mesenchyme
detected detected
3rd branchial groove ectoderm
detected detected
3rd branchial arch mesenchyme
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1345256
Entity Detected:Spry2, sprouty homolog 2 (Drosophila) ( MGI:1345138)
Notes:The Spry2 probe used in this study by Lin et al., 2002 [PMID:11960706] i indicated as that originally described in Minowada et al., 1999 [PMID:10498682] and corresponds to "the complete protein coding region and 3'UTR". The exact end positions of the clone are unspecified.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Strain:CD-1
Age:9.75 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Lin W; Furthauer M; Thisse B; Thisse C; Jing N; Ang SL, 2002 [PMID:11960706] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S0925-4773(02)00018-7] [ PMID:11960706] Lin W, F�rthauer M, Thisse B, Thisse C, Jing N, Ang SL 2002 Cloning of the mouse Sef gene and comparative analysis of its expression with Fgf8 and Spry2 during embryogenesis. Mech Dev (113):163-8
 [ PMID:10498682] Minowada G, Jarvis LA, Chi CL, Neubuser A, Sun X, Hacohen N, Krasnow MA, Martin GR 1999 Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed. Development (1999):4465-75
Links:MGI:3040286 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI