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EMAGE:465

Hgf hepatocyte growth factor ( MGI:96079)
TS17 (10.5 Theiler Stage)
in situ hybridisation

Data Images
EMAGE:465
Figure 4C of Dietrich et al., 1999 [PMID:10079225] . Copyright: This image is from Development and is displayed with permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Arrow points to the center of the first branchial arch.
Expression Pattern Description
Spatial Annotation:
EMAGE:465EMAGE:465Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D context movie

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
465_voxel_strong_3D_1.wlz
465_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:465_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
1st branchial arch
detected detected
regionalExpression is detected in a path from the occipital somites to the center of the first branchial arch.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1333109
Entity Detected:Hgf, hepatocyte growth factor ( MGI:96079)
Notes:The Hgf (SF/HGF) probe used in this study by Dietrich et al., 1999 [PMID:10079225] is indicated as that described by Sonnenberg et al., 1993 [PMID:8408200] . Sonnenberg et al used three Hgf probes: mSF1, mSF2 and mSF3 (see Fig. 1 therein for a map), corresponding to positions 75-465, 676-975, and 1104-2634 in the human cDNA (respectively); Weidner et al., 1991 [PMID:1831266] ". It is unclear which was used here.
Chemistry:RNA
Strand:antisense
Label:S35
Specimen
Organism:mouse
Strain:129P2/Ola x C57BL/6
Age:10.5 Theiler Stage
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:section
Procedures
Embedding:cryosection
Staining procedure:autoradiography
General Information
Authors:Dietrich et al., 1999 [PMID:10079225] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1083/jcb.123.1.223] [ PMID:8408200] Sonnenberg E, Meyer D, Weidner KM, Birchmeier C 1993 Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development. J Cell Biol (123):223-35
 [ PMID:10079225] Dietrich S, Abou-Rebyeh F, Brohmann H, Bladt F, Sonnenberg-Riethmacher E, Yamaai T, Lumsden A, Brand-Saberi B, Birchmeier C 1999 The role of SF/HGF and c-Met in the development of skeletal muscle. Development (126):1621-9
 [ doi:10.1073/pnas.88.16.7001] [ PMID:1831266] Weidner KM, Arakaki N, Hartmann G, Vandekerckhove J, Weingart S, Rieder H, Fonatsch C, Tsubouchi H, Hishida T, Daikuhara Y 1991 Evidence for the identity of human scatter factor and human hepatocyte growth factor. Proc Natl Acad Sci U S A (88):7001-5
Links:MGI:1333516 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI