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EMAGE:4658

Arx aristaless related homeobox ( MGI:1097716)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:4658
Fig1e. Copyright: This image is from [doi:10.1002/dvdy.20164] Colombo E; Galli R; Cossu G; Gecz J; Broccoli V, "Mouse orthologue of ARX, a gene mutated in several X-linked forms of mental retardation and epilepsy, is a marker of adult neural stem cells and forebrain GABAergic neurons." Dev Dyn 2004 Nov;231(3):631-639, and is displayed with the permission of Wiley-Liss, Inc. who owns the Copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: Arrow indicates the posterior boundary in the most caudal forebrain; fb - forebrain; hb - hindbrain; md - midbrain.
Expression Pattern Description
Spatial Annotation:
EMAGE:4658Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4658_wholemount_moderate_3D_1.wlz
4658_wholemount_weak_3D_1.wlz
4658_wholemount_notDetected_3D_1.wlz
4658_wholemount_strong_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4658_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
telencephalic vesicle
detected detected
Arx expression spreads more anteriorly into the telencephalic vesicles at this stage.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Arx probeA
Entity Detected:Arx, aristaless related homeobox ( MGI:1097716)
Notes:The Arx probe used in this study by Colombo et al., 2004 [PMID:15376319] is of unreported sequence.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
Staining procedure:alkaline phosphatase + BMpurple
General Information
Authors:Colombo E; Galli R; Cossu G; Gecz J; Broccoli V, 2004 [PMID:15376319] , Indexed and Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1002/dvdy.20164] [ PMID:15376319] Colombo E, Galli R, Cossu G, Gecz J, Broccoli V 2004 Mouse orthologue of ARX, a gene mutated in several X-linked forms of mental retardation and epilepsy, is a marker of adult neural stem cells and forebrain GABAergic neurons. Dev Dyn (231):631-9
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE