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EMAGE:4662

Apoe apolipoprotein E ( MGI:88057)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:4662
Fig2G. from [PMID:10221153] Biofactors 1999 9(1): 11-17, Bachner D; Schroder D; Betat N; Ahrens M; Gross G, Apolipoprotein E (ApoE), a Bmp-2 (bone morphogenetic protein) upregulated gene in mesenchymal progenitors (C3H10T1/2), is highly expressed in murine embryonic development. Copyright 1999.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:4662Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4662_wholemount_possible.wlz
4662_wholemount_notDetected.wlz
4662_wholemount_strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4662_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
lung
detected detected
biliary bud
detected detected
Expressed in liver.
heart
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Apoe probeA
Entity Detected:Apoe, apolipoprotein E ( MGI:88057)
Notes:The Apoe probe used in this study by Bachner et al., 1999 [PMID:10221153] is of unreported sequence. Method of Rosen & Beddington [PMID:8337752] used.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Strain:NMRI
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
Staining procedure:alkaline phosphatase + NBT/BCIP
General Information
Authors:Bachner D; Schroder D; Betat N; Ahrens M; Gross G, 1999 [PMID:10221153] , Indexed and Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1002/biof.5520090103] [ PMID:10221153] Bachner D, Schroder D, Betat N, Ahrens M, Gross G 1999 Apolipoprotein E (ApoE), a Bmp-2 (bone morphogenetic protein) upregulated gene in mesenchymal progenitors (C3H10T1/2), is highly expressed in murine embryonic development. Biofactors (9):11-7
 [ doi:10.1016/0168-9525(93)90162-B] [ PMID:8337752] Rosen B, Beddington RS 1993 Whole-mount in situ hybridization in the mouse embryo: gene expression in three dimensions. Trends Genet (9):162-7
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE