EMAGE mouse gene expression spatial database

EMAGE:4665

Atf6 activating transcription factor 6 ( MGI:1926157)
TS18 (9.75 dpc)
in situ reporter

Data Images


Fig3C(top). from [doi:10.1074/jbc.M505784200] [PMID:16452489] J Biol Chem 2006 281(13): 8877-8887, Mao C; Tai WC; Bai Y; Poizat C; Lee AS, In vivo regulation of Grp78/BiP transcription in the embryonic heart: role of the endoplasmic reticulum stress response element and GATA-4. Copyright 2006

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Expression Pattern Description

Spatial Annotation:

Annotation colour key:

wholemount mapping

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Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

embryo

strong

homogeneous

beta-galactosidase activity driven by the ATF6 promoter was ubiquitously and highly expressed in the whole embryo (Fig. 3C and data not shown).

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ reporter
Entity Detected:	Atf6, activating transcription factor 6 ( MGI:1926157)
Notes:	Atf6 expression was detected in this study by Mao et al., 2006 [PMID:16452489] using an ATF6/beta-geo insertional mutation mouse generously provided by Dr. William Skarnes (Wellcome Trust Sanger Institute), its generation has been described (Skarnes et al., 1995 [PMID:7604039] ).
Labelled with:	LacZ

Specimen

Procedures

Fixation:

4% paraformaldehyde

General Information

Authors:	Mao C; Tai WC; Bai Y; Poizat C; Lee AS, 2006 [PMID:16452489] , Indexed by GXD, Spatially Mapped by EMAGE.
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ doi:10.1074/jbc.M505784200] [ PMID:16452489] Mao C, Tai WC, Bai Y, Poizat C, Lee AS 2006 In vivo regulation of Grp78/BiP transcription in the embryonic heart: role of the endoplasmic reticulum stress response element and GATA-4. J Biol Chem (281):8877-87
	[ doi:10.1073/pnas.92.14.6592] [ PMID:7604039] Skarnes WC, Moss JE, Hurtley SM, Beddington RS 1995 Capturing genes encoding membrane and secreted proteins important for mouse development. Proc Natl Acad Sci U S A (92):6592-6
Links:	MGI:3655482 same experiment
	MGI:3655486 allele description
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source