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EMAGE:4699

Myl7 myosin, light polypeptide 7, regulatory ( MGI:107495)
TS15 (9.25 dpc)
in situ hybridisation

Data Images
EMAGE:4699
Fig 3A. Copyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.2001.0417] [PMID:11784028] Dev Biol 239(2): 190-203. Yamagishi H; Yamagishi C; Nakagawa O; Harvey RP; Olson EN; Srivastava D; The Combinatorial Activities of Nkx2.5 and dHAND Are Essential for Cardiac Ventricle Formation. Copyright 2001.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: a, atrial chamber; lv, left ventricle.
Expression Pattern Description
Spatial Annotation:
EMAGE:4699Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4699_wholemount_notDetected_3D_1.wlz
4699_wholemount_strong_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4699_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
primitive ventricle
detected detected
heart atrium
detected detected
heart
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Myl7 probeA
Entity Detected:Myl7, myosin, light polypeptide 7, regulatory ( MGI:107495)
Notes:The Myl7 (MLC2A) probe template clone used in this study by Yamagishi et al., 2001 [PMID:11784028] is indicated as that used by Furilli et al, 1998 [PMID:9500550] , who in turn refer to Srivastava et al, 1995 [PMID:8533092] . Editors Note: There is no mention of a MLC2A probe made by Srivastava et al.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:9.25 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Yamagishi H; Yamagishi C; Nakagawa O; Harvey RP; Olson EN; Srivastava D, 2001 [PMID:11784028] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1006/dbio.2001.0417] [ PMID:11784028] Yamagishi H, Yamagishi C, Nakagawa O, Harvey RP, Olson EN, Srivastava D 2001 The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation. Dev Biol (239):190-203
 [ doi:10.1038/ng0398-266] [ PMID:9500550] Firulli AB, McFadden DG, Lin Q, Srivastava D, Olson EN 1998 Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1. Nat Genet (18):266-70
 [ doi:10.1126/science.270.5244.1995] [ PMID:8533092] Srivastava D, Cserjesi P, Olson EN 1995 A subclass of bHLH proteins required for cardiac morphogenesis. Science (270):1995-9
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE