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EMAGE:4717

Nkx3-2 NK3 homeobox 2 ( MGI:108015)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:4717
Figure 3E. Copyright: This image is from Rodrigo I; Hill RE; Balling R; Munsterberg A; Imai K, Development 2003 Feb;130(3):473-82 [doi:10.1242/dev.00240] and is displayed with the permission of The Company of Biologist Limited who owns the Copyright. [PMID:12490554]

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:4717Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4717_wholemount_notDetected_3D_1.wlz
4717_wholemount_strong_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4717_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
trunk somite
detected detected
regionalExpressed in sclerotomes.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Nkx3-2 probeA
Entity Detected:Nkx3-2, NK3 homeobox 2 ( MGI:108015)
Notes:The Nkx3-2 probe used in this study by Rodrigo et al., 2003 [PMID:12490554] is indicated as that used by Lettice et al., 2001 [PMID:11523821] . Editors note: Lettice et al. show in situ hybridisation results for Bapx1, but not report any information regarding the probe.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Staining procedure:alkaline phosphatase + BMpurple
General Information
Authors:Rodrigo I; Hill RE; Balling R; Munsterberg A; Imai K, 2003 [PMID:12490554] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1242/dev.00240] [ PMID:12490554] Rodrigo I, Hill RE, Balling R, M�nsterberg A, Imai K 2003 Pax1 and Pax9 activate Bapx1 to induce chondrogenic differentiation in the sclerotome. Development (130):473-82
 [ PMID:11523821] Lettice L, Hecksher-S�rensen J, Hill R 2001 The role of Bapx1 (Nkx3.2) in the development and evolution of the axial skeleton. J Anat (199):181-7
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE