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EMAGE:4722

Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 ( MGI:1353450)
TS17 (10.5 dpc)
immunohistochemistry

Data Images
EMAGE:4722
Fig3C. from [PMID:10585298] Exp Cell Res 253: 737-746, Wallen A; Zetterstrom RH; Solomin L; Arvidsson M; Olson L; Perlmann T, Fate of mesencephalic AHD2-expressing dopamine progenitor cells in NURR1 mutant mice. Copyright 1999

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:4722Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4722_wholemount_moderate_3D_1.wlz
4722_wholemount_weak_3D_1.wlz
4722_wholemount_notDetected_3D_1.wlz
4722_wholemount_strong_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4722_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
midbrain
strong strong
gradedAHD2 is expressed in a rostro-caudal gradient in the mesencephalic flexure, being stronger in more caudal parts.
optic cup
detected detected
regionalExpressed in dorsal retina
Annotation Validation: EMAGE Editor
Detection Reagent
Type:antibody
Identifier:Aldh1a1 antibodyA
Entity Detected:Aldh1a1, aldehyde dehydrogenase family 1, subfamily A1 ( MGI:1353450)
Notes:The anti-Aldh1a1 (anti-AHD2) antibody used in this study by Wallen et al., 1999 [PMID:10585298] is described as "(anti-AHD2 1:400)".
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Visualisation method:Vectastain ABC
General Information
Authors:Wallen A; Zetterstrom RH; Solomin L; Arvidsson M; Olson L; Perlmann T, 1999 [PMID:10585298] , Indexed and Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1006/excr.1999.4691] [ PMID:10585298] Wallen A, Zetterstrom RH, Solomin L, Arvidsson M, Olson L, Perlmann T 1999 Fate of mesencephalic AHD2-expressing dopamine progenitor cells in NURR1 mutant mice. Exp Cell Res (253):737-46
 [ doi:10.1101/gad.11.15.1925] [ PMID:9271116] Qiu Y, Pereira FA, DeMayo FJ, Lydon JP, Tsai SY, Tsai MJ 1997 Null mutation of mCOUP-TFI results in defects in morphogenesis of the glossopharyngeal ganglion, axonal projection, and arborization. Genes Dev (11):1925-37
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE