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EMAGE:4723

Casp3 caspase 3 ( MGI:107739)
TS18 (10.5 dpc)
immunohistochemistry

Data Images
EMAGE:4723
Fig7B. [doi:10.1186/1471-213X-6-56] [PMID:17116257] Copyright: This image is from Andrieu D; Meziane H; Marly F; Angelats C; Fernandez PA; Muscatelli F, BMC Dev Biol 2006:8, an open-access article distributed under the terms of the Creative Commons Attribution License

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Caspase 3 immunostaining is used in this study as an indicator of cell death.
Expression Pattern Description
Spatial Annotation:
EMAGE:4723Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4723_wholemount_possible.wlz
4723_wholemount_notDetected.wlz
4723_wholemount_strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4723_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
embryo
detected detected
Cell death in early embryos at E10.5 was assessed by Caspase3-immunostaining
Annotation Validation: EMAGE Editor
Detection Reagent
Type:antibody
Identifier:Casp3 antibodyA
Entity Detected:Casp3, caspase 3 ( MGI:107739)
Notes:The anti-Caspase-3-activated (Casp3) antibody used in this study by Andrieu et al., 2006 [PMID:17116257] is not described by the authors.
Specimen
Organism:mouse
Strain:C57BL/6
Age:10.5 dpc
Theiler Stage:TS18
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Andrieu D; Meziane H; Marly F; Angelats C; Fernandez PA; Muscatelli F, 2006 [PMID:17116257] , Indexed and Spatially Mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1186/1471-213X-6-56] [ PMID:17116257] Andrieu D, Meziane H, Marly F, Angelats C, Fernandez PA, Muscatelli F 2006 Sensory defects in Necdin deficient mice result from a loss of sensory neurons correlated within an increase of developmental programmed cell death. BMC Dev Biol (6):56
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE