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EMAGE:4741

Nr2f2 nuclear receptor subfamily 2, group F, member 2 ( MGI:1352452)
TS15 (9.75 dpc)
in situ hybridisation

Data Images
EMAGE:4741
Figure 1F. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2005.03.012] Gene Expr Patterns 5: 587-92, Tang LS; Alger HM; Lin F; Pereira FA, "Dynamic expression of COUP-TFI and COUP-TFII during development and functional maturation of the mouse inner ear." Copyright 2005. [PMID:15907456]

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: arrowhead, ventral-anterior domain of otic placode.
Expression Pattern Description
Spatial Annotation:
EMAGE:4741Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4741_wholemount_moderate_3D_1.wlz
4741_wholemount_weak_3D_1.wlz
4741_wholemount_notDetected_3D_1.wlz
4741_wholemount_strong_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4741_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
ear
detected detected
regionalExpressed in the ventral-anterior domain of the invaginating otic placode epithelium with expanded expression posteriorly.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Nr2f2 probeA
Entity Detected:Nr2f2, nuclear receptor subfamily 2, group F, member 2 ( MGI:1352452)
Notes:The Nr2f2 (COUP-TFII) probe template used in this study by Tang et al., 2005 [PMID:15907456] was a "COUP-TFII cDNA (kindly provided by Dr. Austin Cooney) (Qiu et al., 1994 [PMID:8183930] )". Qiu et al. describe it as "The template cDNA encoding the whole open reading frame of mCOUP-TFII was subcloned into pBluescript SK+."
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Strain:129/SvEv
Age:9.75 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Tang LS; Alger HM; Lin F; Pereira FA, 2005 [PMID:15907456] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/j.modgep.2005.03.012] [ PMID:15907456] Tang LS, Alger HM, Lin F, Pereira FA 2005 Dynamic expression of COUP-TFI and COUP-TFII during development and functional maturation of the mouse inner ear. Gene Expr Patterns (5):587-92
 [ doi:10.1073/pnas.91.10.4451] [ PMID:8183930] Qiu Y, Cooney AJ, Kuratani S, DeMayo FJ, Tsai SY, Tsai MJ 1994 Spatiotemporal expression patterns of chicken ovalbumin upstream promoter-transcription factors in the developing mouse central nervous system: evidence for a role in segmental patterning of the diencephalon. Proc Natl Acad Sci U S A (91):4451-5
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE