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EMAGE:4745

Nrg2 neuregulin 2 ( MGI:1098246)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:4745
Fig2b. [doi:10.1038/387512a0] Carraway KL 3rd; Weber JL; Unger MJ; Ledesma J; Yu N; Gassmann M; Lai C, "Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases." Nature (1997) 387: 512-6. [PMID:9168115] © Nature Publishing Group. Reproduced with permission from Nature.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: A, atrium; V, ventricle.
Expression Pattern Description
Spatial Annotation:
EMAGE:4745Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4745_wholemount__moderate.wlz
4745_wholemount__possible.wlz
4745_wholemount__notDetected.wlz
4745_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4745_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
heart atrium
strong strong
primitive ventricle
moderate moderate
outflow tract
moderate moderate
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Nrg2 probeA
Entity Detected:Nrg2, neuregulin 2 ( MGI:1098246)
Notes:The Nrg2 probe used in this study by Carraway et al., 1997 [PMID:9168115] was "a 768-nucleotide insert corresponding to residues 11-267 of the assembled protein sequence" (see Figure 1a therein). Editor's note: When this EMAGE entry was made (17 June 2008), there were no cDNA nucleotide sequences for mouse Nrg2 deposited in GenBank that covered this entire region.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Carraway KL 3rd; Weber JL; Unger MJ; Ledesma J; Yu N; Gassmann M; Lai C, 1997 [PMID:9168115] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1038/387512a0] [ PMID:9168115] Carraway KL, Weber JL, Unger MJ, Ledesma J, Yu N, Gassmann M, Lai C 1997 Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases. Nature (387):512-6
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE