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EMAGE:4746

Nrg3 neuregulin 3 ( MGI:1097165)
TS17 (38 Somite no.)
in situ hybridisation

Data Images
EMAGE:4746
Figure 3A. [doi:10.1101/gad.338505] Howard B; Panchal H; McCarthy A; Ashworth A, "Identification of the scaramanga gene implicates Neuregulin3 in mammary gland specification." Genes Dev (2005) 19: 2078-90. [PMID:16140987]

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:4746Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4746_wholemount_possible_3D_1.wlz
4746_wholemount_notDetected_3D_1.wlz
4746_wholemount_strong_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4746_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
embryo
detected detected
regionalExpression underlying the future site of number 3 mammary gland at the level of somite 18.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Nrg3 probeA
Entity Detected:Nrg3, neuregulin 3 ( MGI:1097165)
Notes:The Nrg3 probe used in this study by Howard et al., 2005 [PMID:16140987] was one of "five Nrg3 probes (corresponding to nucleotides 1-680, 1242-1850, 1923-2538, 827-1321 for exons 2-3, and 1435-1922 of GenBank accession no. NM_008734) ... All Nrg3 anti-sense probes gave similar results". Editors note: it is unspecified which particular probe was used for this assay.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Strain:either: B6 or A/J
Age:38 Somite no.
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Howard B; Panchal H; McCarthy A; Ashworth A, 2005 [PMID:16140987] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1101/gad.338505] [ PMID:16140987] Howard B, Panchal H, McCarthy A, Ashworth A 2005 Identification of the scaramanga gene implicates Neuregulin3 in mammary gland specification. Genes Dev (19):2078-90
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE