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EMAGE:4762

Pbrm1 polybromo 1 ( MGI:1923998)
TS18 (11.5 dpc)
in situ reporter

Data Images
EMAGE:4762
Figure 2A. [doi:10.1101/gad.1238104] Wang Z; Zhai W; Richardson JA; Olson EN; Meneses JJ; Firpo MT; Kang C; Skarnes WC; Tjian R, "Polybromo protein BAF180 functions in mammalian cardiac chamber maturation." Genes Dev (2004) 18: 3106-16. [PMID:15601824]

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:4762Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4762_wholemount_moderate_3D_1.wlz
4762_wholemount_possible_3D_1.wlz
4762_wholemount_strong_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4762_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
embryo
detected detected
homogeneousExpression is ubiquitous.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ reporter
Entity Detected:Pbrm1, polybromo 1 ( MGI:1923998)
Notes:Pbrm1 (BAF180) expression was detected in this study by Vauti et al., 2007 [PMID:17198746] in heterozygous embryos generated using a knock-in approach whereby a genomic fragment containing predicted exon 11 was replaced with an in frame beta-galactosidase-neomycin phosphotransferase fusion gene (beta-geo). A fusion protein is expressed under the contol of the endogenous gene promoter. See Figure 1 therein for further details.
Labelled with:LacZ
Specimen
Organism:mouse
Age:11.5 dpc
Theiler Stage:TS18
Mutations:Pbrmtm1Rtj/Pbrm1+
Preparation:wholemount
Procedures
General Information
Authors:Wang Z; Zhai W; Richardson JA; Olson EN; Meneses JJ; Firpo MT; Kang C; Skarnes WC; Tjian R, 2004 [PMID:15601824] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1101/gad.1238104] [ PMID:15601824] Wang Z, Zhai W, Richardson JA, Olson EN, Meneses JJ, Firpo MT, Kang C, Skarnes WC, Tjian R 2004 Polybromo protein BAF180 functions in mammalian cardiac chamber maturation. Genes Dev (18):3106-16
Links:MGI:3526660 allele description
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE