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EMAGE:4767

Pdgfrb platelet derived growth factor receptor, beta polypeptide ( MGI:97531)
TS17 (10.5 dpc)
in situ reporter

Data Images
EMAGE:4767
Figure 2C. Soriano P, "Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice." Genes Dev (1994) 8: 1888-96. [PMID:7958864]

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:4767Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4767_wholemount_moderate_3D_1.wlz
4767_wholemount_weak_3D_1.wlz
4767_wholemount_notDetected_3D_1.wlz
4767_wholemount_strong_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4767_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
forelimb bud mesenchyme
detected detected
hindlimb bud mesenchyme
detected detected
trunk somite
detected detected
heart
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ reporter
Entity Detected:Pdgfrb, platelet derived growth factor receptor, beta polypeptide ( MGI:97531)
Notes:Pdgfrb (PDGF-beta-3R) expression was detected in this study by Soriano, 1994 [PMID:7958864] in heterozygote mutant embryos that were generated using a targeting strategy whereby a promoterless beta-galactosidase/neomycin gene fusion (beta-geo) was inserted in frame into the exon coding for the signal peptide. Southern blot analysis demonstrated that three tandem copies of the beta-geo gene were present in a concatamer.
Labelled with:LacZ
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:Pdgfrbtm2Sor/Pdgfrb+
Preparation:wholemount
Procedures
General Information
Authors:Soriano P, 1994 [PMID:7958864] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1101/gad.8.16.1888] [ PMID:7958864] Soriano P 1994 Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice. Genes Dev (8):1888-96
Links:MGI:2135519 allele description
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE