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EMAGE:4791

Psen1 presenilin 1 ( MGI:1202717)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:4791
Fig4G. [doi:10.1038/387288a0] Wong PC; Zheng H; Chen H; Becher MW; Sirinathsinghji DJ; Trumbauer ME ; Chen HY ; Price DL ; Van der Ploeg LH ; Sisodia SS, "Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm." Nature (1997) 387: 288-92. [PMID:9153393] © Nature Publishing Group. Reproduced with permission from Nature.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: arrows point to somites and the bracket indicates the presomitic mesoderm.
Expression Pattern Description
Spatial Annotation:
EMAGE:4791Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4791_wholemount__possible.wlz
4791_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4791_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
tail unsegmented mesenchyme
detected detected
Expressed in presomitic mesoderm
trunk somite
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Psen1 probeA
Entity Detected:Psen1, presenilin 1 ( MGI:1202717)
Notes:The Psen1 (PS1) probe used in this study by Wong et al., 1997 [PMID:9153393] is of unreported sequence.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Wong PC; Zheng H; Chen H; Becher MW; Sirinathsinghji DJ; Trumbauer ME ; Chen HY ; Price DL ; Van der Ploeg LH ; Sisodia SS, 1997 [PMID:9153393] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1038/387288a0] [ PMID:9153393] Wong PC, Zheng H, Chen H, Becher MW, Sirinathsinghji DJ, Trumbauer ME, Chen HY, Price DL, Van der Ploeg LH, Sisodia SS 1997 Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm. Nature (387):288-92
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE