EMAGE mouse gene expression spatial database

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EMAGE:482

Serpine2 serine (or cysteine) peptidase inhibitor, clade E, member 2 ( MGI:101780)
TS17 (10.5 dpc)
in situ hybridisation

Data Images


Fig1B, Kury et al, 1997 [PMID:9102311] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd who owns the copyright.

Expression pattern clarity:
Find spatially similar wholemount expression patterns:

Notes:

Image annotations: mm, met-/mesencephalic junction; m, mesencephalon.

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

wholemount mapping

Download individual expression domains:

482_wholemount_strong_3D_1.wlz

482_wholemount_weak_3D_1.wlz

482_wholemount_notDetected_3D_1.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:482_all_domains.zip

Find spatially similar wholemount expression patterns:

EMAGE spatially similar wholemount patterns

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

midbrain

detected

regional

A band of neuroepithelial cells surrounding the neural tube at the level of the junction between the met- and mesencephalon was observed. PN-1 mRNA was also observed in the ventral part of the mes- and diencephalon

diencephalon

detected

regional

PN-1 mRNA was also observed in the ventral part of the mes- and diencephalon

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	MGI:1335333
Entity Detected:	Serpine2, serine (or cysteine) peptidase inhibitor, clade E, member 2 ( MGI:101780)
Sequence:	sense strand is shown >MGI:1335333 GGATCCAGGTCTTCAATCAGATCATCAAGTCACGGCCTCATGAGAACGTTGTTGTCTCCCCACATGGGAT CGCGTCCATCTTGGGCATGCTGCAGCTCGGGGCTGACGGCAAGACAAAGAAGCAGCTCTCCACGGTGATG CGATATAATGTAAACGGAGTTGGTAAAGTGCTGAAGAAGATCAACAAGGCTATTGTCTCCAAGAAAAATA AAGACATTGTGACCGTGGCCAATGCTGTGTTTCTCAGGAATGGCTTTAAAATGGAAGTGCCTTTTGCAGT AAGGAACAAAGATGTGTTTCAGTGTGAAGTGCAGAATGTGAACTTCCAGGACCCAGCCTCTGCCTCTGAG TCCATCAATTTTTGGGTCAAAAATGAGACCAGGGGCATGATTGATAATCTGCTTTCCCCAAATCTGATCG ATGGTGCCCTTACCAGGCTGGTCCTCGTTAATGCAGTGTATTTCAAGGGTTTGTGGAAGTCTCGGTTTCA ACCAGAGAGCACAAAGAAACGGACATTCGTGGCAGGTGATGGGAAATCCTACCAAGTACCCATGTTGGCT CAGCTCTCTGTGTTCCGCTCAGGGTCTACCAGGACCCCGAATGGCTTATGGTACAACTTCATTGAGCTGC CCTACCATGGTGAGAGCATCAGCATGCTGATCGCCCTGCCAACAGAGAGCTCCACCCCACTGTCTGCCAT CATCCCTCACATCACTACCAAGACCATTGATAGCTGGATGAACACCATGGTACCCAAGAGGATGCAGCTG GTCCTACCCAAGTTCACAGCTGTGGCACAAACAGATCTGAAGGAGCCACTGAAAGCCCTTGGCATTACTG AGATGTTTGAGCCATCAAAGGCAAATTTTACAAAAATAACAAGGTCAGAGAGCCTTCATGTCTCTCACAT CTTGCAAAAAGCAAAAATTGAAGTCAGTGAAGATGGAACCAA
	nt 253 - nt 1204 of NM_009255.2
Notes:	The Serpine2 (PN-1) probe used in this study by Kury et al, 1997 [PMID:9102311] is defined as a "951 bp fragment (BamHI-HindIII) spanning the central part of the mouse PN-1 gene"
Chemistry:	RNA
Strand:	antisense
Label:	digoxigenin

Specimen

Organism:	mouse
Age:	10.5 dpc
Theiler Stage:	TS17
Mutations:	none (wild-type)
Preparation:	wholemount

Procedures

Fixation:

4% paraformaldehyde

General Information

Authors:	Kury et al, 1997 [PMID:9102311] Indexed by GXD, Spatially mapped by EMAGE
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ PMID:9102311] Kury P, Schaeren-Wiemers N, Monard D 1997 Protease nexin-1 is expressed at the mouse met-/mesencephalic junction and FGF signaling regulates its promoter activity in primary met-/mesencephalic cells. Development (124):1251-62
Links:	MGI:1335376 same experiment
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source