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EMAGE:4829

Cdon cell adhesion molecule-related/down-regulated by oncogenes ( MGI:1926387)
TS18 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:4829
Fig1D. Copyright: This image is from [doi:10.1002/1097-0177(2000)9999:9999<::AID-DVDY1032>3.0.CO;2-M] Mulieri PJ; Okada A; Sassoon DA; McConnell SK; Krauss RS, "Developmental expression pattern of the cdo gene." Dev Dyn 2000 Sep;219(1):40-9. Reprinted with permission of Wiley-Liss Inc. [PMID:10974670] .

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: large arrow - expression in the anterior of the limb buds; small arrow - expression in the eye, arrowhead - expression in the otic vesicle; b - branchial arches; lb - limb bud; t - telencephalon.
Expression Pattern Description
Spatial Annotation:
EMAGE:4829Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4829_wholemount_moderate_3D_1.wlz
4829_wholemount_weak_3D_1.wlz
4829_wholemount_notDetected_3D_1.wlz
4829_wholemount_strong_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4829_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
neural tube
detected detected
regionalExpression is maintained in the dorsal neural tube.
trunk somite
detected detected
head mesenchyme
detected detected
regionalexpression is detected in head mesenchyme in the region of the nasal processes.
limb
detected detected
regionalExpression also can be detected in the anterior of the limb buds.
telencephalon
detected detected
branchial arch
detected detected
eye
detected detected
ear
detected detected
Expression also can be detected in the otic vesicle.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Cdon probeA
Entity Detected:Cdon, cell adhesion molecule-related/down-regulated by oncogenes ( MGI:1926387)
Notes:The Cdon (cdo) probe used in this study by Mulieri et al., 2000 [PMID:10974670] is described as follows: "Digestion of a mouse cdo cDNA clone in pBluescript(KS-) (Stratagene, La Jolla, CA) with XhoI generated a linearized, 2.4-kb DNA template encompassing part of the fifth Ig domain, all three FNIII repeats, the transmembrane and intracellular domains, and approximately 300-bp of 3'UTR."
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS18
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
Staining procedure:alkaline phosphatase + BMpurple
General Information
Authors:Mulieri PJ; Okada A; Sassoon DA; McConnell SK; Krauss RS, 2000 [PMID:10974670] , Indexed Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1002/1097-0177(2000)9999:9999<::AID-DVDY1032>3.0.CO;2-M] [ PMID:10974670] Mulieri PJ, Okada A, Sassoon DA, McConnell SK, Krauss RS 2000 Developmental expression pattern of the cdo gene. Dev Dyn (219):40-9
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE