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EMAGE:4845

Cradd CASP2 and RIPK1 domain containing adaptor with death domain ( MGI:1336168)
TS17 (10.5 dpc)
in situ reporter

Data Images
EMAGE:4845
Fig3b(10.5_Raidd+/-). from [doi:10.1007/s11248-004-2822-7] Transgenic Res 14(1): 27-40, Motaln H; McWhir J; Horvat S, In situ analysis of Raidd-beta-galactosidase fusion gene expression in transgenic mouse midgestation embryos. Copyright 2005 [PMID:15865046]

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:4845Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4845_wholemount_moderate_3D_1.wlz
4845_wholemount_notDetected_3D_1.wlz
4845_wholemount_strong_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4845_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
heart
detected detected
regionalExpression is seen in the cardiac and pericardial region.
1st branchial arch
detected detected
regionalExpression becomes evident ventrally in the first and second branchial arch region of the head.
2nd branchial arch
detected detected
regionalExpression becomes evident ventrally in the first and second branchial arch region of the head.
embryo
detected detected
regionalExpression is detected in the whole abdominal side of the embryo just beneath the forelimb bud.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ reporter
Entity Detected:Cradd, CASP2 and RIPK1 domain containing adaptor with death domain ( MGI:1336168)
Notes:Cradd (Raidd) expression was detected in this study by Motaln et al., 2005 [PMID:15865046] in embryos heterozygote for a targeted allele whereby an IRES-Betageo with a loxP site was inserted to replace exons 2 and 3 (which contain the translation start site and the caspase recruiting domain).
Labelled with:LacZ
Specimen
Organism:mouse
Strain:involves: 129P2/OlaHsd * C57BL/6J
Age:10.5 dpc
Theiler Stage:TS17
Mutations:Craddtm1Shor/Cradd+
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Motaln H; McWhir J; Horvat S, 2005 [PMID:15865046] , Indexed and Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1007/s11248-004-2822-7] [ PMID:15865046] Motaln H, McWhir J, Horvat S 2005 In situ analysis of Raidd-beta-galactosidase fusion gene expression in transgenic mouse midgestation embryos. Transgenic Res (14):27-40
Links:MGI:3574369 allele description
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE