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EMAGE:4857

Ctnnb1 catenin (cadherin associated protein), beta 1 ( MGI:88276)
TS19 (11.5 dpc)
in situ hybridisation

Data Images
EMAGE:4857
Fig 5A. Copyright: This image is from Chu EY; Hens J; Andl T; Kairo A; Yamaguchi TP; Brisken C; Glick A; Wysolmerski JJ; Millar SE, Development 2004;131(19):4819-29 [doi:10.1242/dev.01347] and is displayed with the permission of The Company of Biologist Limited who owns the Copyright. [PMID:15342465]

Expression pattern clarity: one star
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotation: signal appears red-brown. arrow indicates mammary region expression.
Expression Pattern Description
Spatial Annotation:
EMAGE:4857Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4857_wholemount_moderate_3D_1.wlz
4857_wholemount_weak_3D_1.wlz
4857_wholemount_notDetected_3D_1.wlz
4857_wholemount_strong_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4857_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
embryo
detected detected
Although beta-catenin mRNA was broadly expressed at E11.5, it was slightly upregulated in the mammary region.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Ctnnb1 probeA
Entity Detected:Ctnnb1, catenin (cadherin associated protein), beta 1 ( MGI:88276)
Notes:The Ctnnb1 (beta-catenin) probe used in this study by Chu et al., 2004 [PMID:15342465] , is indicated as that previously described by Mucenski et al., 2003 [PMID:12885771] i.e. "a 324-bp mouse cDNA subcloned into pCRII, Invitrogen."
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:11.5 dpc
Theiler Stage:TS19
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Chu EY; Hens J; Andl T; Kairo A; Yamaguchi TP; Brisken C; Glick A; Wysolmerski JJ; Millar SE, 2004 [PMID:15342465] , Indexed and Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1242/dev.01347] [ PMID:15342465] Chu EY, Hens J, Andl T, Kairo A, Yamaguchi TP, Brisken C, Glick A, Wysolmerski JJ, Millar SE 2004 Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis. Development (131):4819-29
 [ doi:10.1074/jbc.M305892200] [ PMID:12885771] Mucenski ML, Wert SE, Nation JM, Loudy DE, Huelsken J, Birchmeier W, Morrisey EE, Whitsett JA 2003 beta-Catenin is required for specification of proximal/distal cell fate during lung morphogenesis. J Biol Chem (278):40231-8
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE