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EMAGE:488

Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 ( MGI:1349394)
TS11 (7.5 dpc)
in situ hybridisation

Data Images
EMAGE:488
Figure 1E of Xue et al., 2001 [PMID:11290295] . Copyright: This image is from Development and is displayed with permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Arrows, from top to bottom, indicate tail, head process and primitive streak.
Expression Pattern Description
Spatial Annotation:
EMAGE:488Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
488_wholemount_strong_3D_1.wlz
488_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:488_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
embryo
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1932892
Entity Detected:Map4k4, mitogen-activated protein kinase kinase kinase kinase 4 ( MGI:1349394)
Notes:The Map4k4 (NIK) probe used in this study by Xue et al., 2001 [PMID:11290295] "corresponds to nucleotides 1347-1845 in full length NIK. This region is located between the kinase domain and C-terminal domain and is the region least conserved between NIK and other Ste20 kinases". Which 'full length' clone is referred to is not indicated therefore exact probe end points are undefined.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Strain:Swiss
Age:7.5 dpc
Theiler Stage:TS11
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Xue et al., 2001 [PMID:11290295] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:11290295] Xue Y, Wang X, Li Z, Gotoh N, Chapman D, Skolnik EY 2001 Mesodermal patterning defect in mice lacking the Ste20 NCK interacting kinase (NIK). Development (128):1559-72
Links:MGI:1933014 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI