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EMAGE:4920

Ret ret proto-oncogene ( MGI:97902)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:4920
Figure 2C. This image is from Natarajan D; Marcos-Gutierrez C; Pachnis V; de Graaff E, Development 2002, 129: 5151-60 and is displayed with the permission of The Company of Biologists Limited who owns the Copyright. [PMID:12399307]

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: enteric nervous system progenitors (white arrowhead); outline of the stomach is indicated by line and an arrow.
Expression Pattern Description
Spatial Annotation:
EMAGE:4920Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4920_wholemount_moderate.wlz
4920_wholemount_possible.wlz
4920_wholemount_notDetected.wlz
4920_wholemount_strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4920_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
foregut
detected detected
regionalForegut invaded by pre-enteric neural crest cells.
peripheral nervous system
detected detected
regionalExpressed in enteric nervous system.
gut
detected detected
regionalExpressed in enteric nervous system.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Ret probeA
Entity Detected:Ret, ret proto-oncogene ( MGI:97902)
Notes:The Ret (c-Ret) probe used in this study by Natarajan et al., 2002 [PMID:12399307] is indicated as "pmcRet7" as reported by Durbec et al., 1996 [PMID:8565847] . Editors Note: Durbec et al do not describe a plasmid called pmcRet7 nor do they report the sequence of the probe used for their Ret in situs.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Natarajan D; Marcos-Gutierrez C; Pachnis V; de Graaff E, 2002 [PMID:12399307] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:12399307] Natarajan D, Marcos-Gutierrez C, Pachnis V, de Graaff E 2002 Requirement of signalling by receptor tyrosine kinase RET for the directed migration of enteric nervous system progenitor cells during mammalian embryogenesis. Development (129):5151-60
 [ PMID:8565847] Durbec PL, Larsson-Blomberg LB, Schuchardt A, Costantini F, Pachnis V 1996 Common origin and developmental dependence on c-ret of subsets of enteric and sympathetic neuroblasts. Development (122):349-58
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE