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EMAGE:4926

Robo2 roundabout homolog 2 (Drosophila) ( MGI:1890110)
TS18 (11 dpc)
in situ hybridisation

Data Images
EMAGE:4926
Figure 4M. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(01)00430-0] Mech Dev 106: 175-80, Vargesson N; Luria V; Messina I; Erskine L; Laufer E, "Expression patterns of Slit and Robo family members during vertebrate limb development." Copyright 2001. [PMID:11472852]

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
This is a hindlimb.
Expression Pattern Description
Spatial Annotation:
EMAGE:4926Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4926_wholemount_moderate.wlz
4926_wholemount_weak.wlz
4926_wholemount_notDetected.wlz
4926_wholemount_strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4926_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
hindlimb bud mesenchyme
detected detected
regionalExpressed in proximal central mesenchyme.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Robo2 probeA
Entity Detected:Robo2, roundabout homolog 2 (Drosophila) ( MGI:1890110)
Notes:The Robo2 probe used in this study by Vargesson et al., 2001 [PMID:11472852] is identified as a rat probe used Brose et al., 1999 [PMID:10102268] . Brose et al state that "in situ analyses were carried out with at least two independent probes, with identical results". Editors note: Neither probe is of reported sequence.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:11 dpc
Theiler Stage:TS18
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Vargesson N; Luria V; Messina I; Erskine L; Laufer E, 2001 [PMID:11472852] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S0925-4773(01)00430-0] [ PMID:11472852] Vargesson N, Luria V, Messina I, Erskine L, Laufer E 2001 Expression patterns of Slit and Robo family members during vertebrate limb development. Mech Dev (106):175-80
 [ doi:10.1016/S0092-8674(00)80590-5] [ PMID:10102268] Brose K, Bland KS, Wang KH, Arnott D, Henzel W, Goodman CS, Tessier-Lavigne M, Kidd T 1999 Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance. Cell (96):795-806
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE