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EMAGE:4932

Rspo3 R-spondin 3 homolog (Xenopus laevis) ( MGI:1920030)
TS16 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:4932 EMAGE:4932 EMAGE:4932 EMAGE:4932 EMAGE:4932
Figure 2C. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.ydbio.2006.08.018] Dev Biol 301: 218-26, Aoki M; Mieda M; Ikeda T; Hamada Y; Nakamura H; Okamoto H, "R-spondin3 is required for mouse placental development." Copyright 2007 [PMID:16963017] Figure 2D. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.ydbio.2006.08.018] Dev Biol 301: 218-26, Aoki M; Mieda M; Ikeda T; Hamada Y; Nakamura H; Okamoto H, "R-spondin3 is required for mouse placental development." Copyright 2007 [PMID:16963017] Figure 2E. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.ydbio.2006.08.018] Dev Biol 301: 218-26, Aoki M; Mieda M; Ikeda T; Hamada Y; Nakamura H; Okamoto H, "R-spondin3 is required for mouse placental development." Copyright 2007 [PMID:16963017] Figure 2F. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.ydbio.2006.08.018] Dev Biol 301: 218-26, Aoki M; Mieda M; Ikeda T; Hamada Y; Nakamura H; Okamoto H, "R-spondin3 is required for mouse placental development." Copyright 2007 [PMID:16963017] Figure 2G. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.ydbio.2006.08.018] Dev Biol 301: 218-26, Aoki M; Mieda M; Ikeda T; Hamada Y; Nakamura H; Okamoto H, "R-spondin3 is required for mouse placental development." Copyright 2007 [PMID:16963017]

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: A, atrium; D, diencephalon; LN, lateral nasal process; MN, medial nasal process; M, midbrain; ov, otic vesicles; S, somites; T, telencephalon; V, ventricle; 1st, first pharyngeal arch. Open triangles indicate the atrioventricular canal of the developing heart (F) or the cephalic mesoderm (D). Closed triangles indicate the roof plate (C, D) or the truncus arteriosus of the developing heart (F). Thick black arrows indicate the pharyngeal arches (G) or a domain surrounding the boundary between the telencephalon and the diencephalon (C, E). Thin black arrows indicate the tail (C) or the tips of the medial nasal processes (G).
Expression Pattern Description
Spatial Annotation:
EMAGE:4932Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4932_wholemount_moderate.wlz
4932_wholemount_possible.wlz
4932_wholemount_notDetected.wlz
4932_wholemount_strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4932_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
tail
detected detected
trunk somite
detected detected
otocyst
detected detected
Expressed in otic vesicles
telencephalon
detected detected
regionalExpression was detected in the medial wall of the dorsal telencephalon, which is a domain surrounding the boundary between the telencephalon and the diencephalon.
diencephalon roof plate
detected detected
Expression is detected in the roof plate throughout the entire neural tube caudal to the telencephalic vesicles
future midbrain roof plate
detected detected
Expression is detected in the roof plate throughout the entire neural tube caudal to the telencephalic vesicles
neural tube roof plate
detected detected
Expression is detected in the roof plate throughout the entire neural tube caudal to the telencephalic vesicles
rhombomere 01 roof plate
detected detected
Expression is detected in the roof plate throughout the entire neural tube caudal to the telencephalic vesicles
rhombomere 02 roof plate
detected detected
Expression is detected in the roof plate throughout the entire neural tube caudal to the telencephalic vesicles
rhombomere 03 roof plate
detected detected
Expression is detected in the roof plate throughout the entire neural tube caudal to the telencephalic vesicles
rhombomere 04 roof plate
detected detected
Expression is detected in the roof plate throughout the entire neural tube caudal to the telencephalic vesicles
rhombomere 05 roof plate
detected detected
Expression is detected in the roof plate throughout the entire neural tube caudal to the telencephalic vesicles
rhombomere 06 roof plate
detected detected
Expression is detected in the roof plate throughout the entire neural tube caudal to the telencephalic vesicles
rhombomere 07 roof plate
detected detected
Expression is detected in the roof plate throughout the entire neural tube caudal to the telencephalic vesicles
rhombomere 08 roof plate
detected detected
Expression is detected in the roof plate throughout the entire neural tube caudal to the telencephalic vesicles
head mesenchyme
detected detected
Expressed in cephalic mesoderm.
heart
detected detected
regionalExpressed in truncus arteriosus
atrioventricular canal
detected detected
branchial arch
detected detected
medial-nasal process
detected detected
forelimb bud
detected detected
regionalat E10.5, expression was observed in a stripe stretching along the proximal-distal axis in the caudal domain (but not at the caudal edge
hindlimb bud
detected detected
regionalat E10.5, expression was observed in a stripe stretching along the proximal-distal axis in the caudal domain (but not at the caudal edge
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Rspo3 probeA
Entity Detected:Rspo3, R-spondin 3 homolog (Xenopus laevis) ( MGI:1920030)
Notes:The Rspo3 probe used in this study by Aoki et al., 2007 [PMID:16963017] is of unreported sequence.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS16
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Aoki M; Mieda M; Ikeda T; Hamada Y; Nakamura H; Okamoto H, 2007 [PMID:16963017] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/j.ydbio.2006.08.018] [ PMID:16963017] Aoki M, Mieda M, Ikeda T, Hamada Y, Nakamura H, Okamoto H 2007 R-spondin3 is required for mouse placental development. Dev Biol (301):218-26
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE