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EMAGE:494

Msx2 homeobox, msh-like 2 ( MGI:97169)
TS18 (11 dpc)
in situ hybridisation

Data Images
EMAGE:494 EMAGE:494
Figure 2B of MacKenzie et al., 1992 [PMID:1358591] . Copyright: This image is from Development and is displayed with permission of The Company of Biologists Ltd. who owns the copyright. Figure 2A of MacKenzie et al., 1992 [PMID:1358591] . Copyright: This image is from Development and is displayed with permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Corresponding darkfield and lightfield images are shown. Abbreviations used: dl, dental lamina; ln, lateral nasal process; mn, medial nasal process; mx, maxillary process; md, mandibular process; nc, nasal cavity. The area of future 1st molar tooth initiation is arrowed.
Expression Pattern Description
Spatial Annotation:
EMAGE:494EMAGE:494Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D context movie

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
494_voxel_strong_3D_1.wlz
494_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:494_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
latero-nasal process mesenchyme
detected detected
medial-nasal process mesenchyme
detected detected
1st branchial arch maxillary component mesenchyme
detected detected
A concentration of expression below the area of future first molar tooth initiation.
1st branchial arch mandibular component mesenchyme
detected detected
regionalExpression in the oral half of the mandibular process.
1st branchial arch mandibular component ectoderm
not detected not detected
1st branchial arch maxillary component ectoderm
not detected not detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:13124
Entity Detected:Msx2, homeobox, msh-like 2 ( MGI:97169)
Notes:The probe used in this study by MacKenzie et al., 1992 [PMID:1358591] is ~0.85kb and contains most of coding region and the 5' half of 3' untranslated region.
Chemistry:RNA
Strand:antisense
Label:S35
Specimen
Organism:mouse
Strain:MF1
Age:11 dpc
Theiler Stage:TS18
Mutations:none (wild-type)
Preparation:section
Procedures
Fixation:4% paraformaldehyde
Embedding:paraffin
Staining procedure:autoradiography
General Information
Authors:MacKenzie et al., 1992 [PMID:1358591] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:1358591] MacKenzie A, Ferguson MW, Sharpe PT 1992 Expression patterns of the homeobox gene, Hox-8, in the mouse embryo suggest a role in specifying tooth initiation and shape. Development (115):403-20
Links:MGI:2136262 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI