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EMAGE:4978

Dbh dopamine beta hydroxylase ( MGI:94864)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:4978
Fig8B. Copyright: Reprinted with permission from Cell Press from [doi:10.1016/S0896-6273(00)80989-7] Neuron 20(3): 483-94, Fode C; Gradwohl G; Morin X; Dierich A; LeMeur M; Goridis C ; Guillemot F , The bHLH protein NEUROGENIN 2 is a determination factor for epibranchial placode-derived sensory neurons. Copyright 1998. [PMID:9539123]

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: ov, otic vesicle; VII, geniculate placode/ganglion; IX, petrosal placode/ganglion; X, nodose placode/ganglion.
Expression Pattern Description
Spatial Annotation:
EMAGE:4978Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4978_wholemount_moderate.wlz
4978_wholemount_possible.wlz
4978_wholemount_notDetected.wlz
4978_wholemount_strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4978_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
facio-acoustic vii-viii preganglion complex
detected detected
regionalDBH is observed in the geniculate (VII) ganglia.
glossopharyngeal ix preganglion
detected detected
regionalDBH is observed in the petrosal (IX) ganglia.
vagus x preganglion
detected detected
regionalDBH is observed in the nodose ganglia (X).
central nervous system ganglion
detected detected
regionalDBH is expressed in the distal ganglionic anlagen.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Dbh probeA
Entity Detected:Dbh, dopamine beta hydroxylase ( MGI:94864)
Notes:The Dbh probe used in this study by Fode et al., 1998 [PMID:9539123] is indicated as that previously described by Morin et al., 1997 [PMID:9115735] which is of unreported sequence.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Fode C; Gradwohl G; Morin X; Dierich A; LeMeur M; Goridis C ; Guillemot F, 1998 [PMID:9539123] , Indexed and Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S0896-6273(00)80989-7] [ PMID:9539123] Fode C, Gradwohl G, Morin X, Dierich A, LeMeur M, Goridis C, Guillemot F 1998 The bHLH protein NEUROGENIN 2 is a determination factor for epibranchial placode-derived sensory neurons. Neuron (20):483-94
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE