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EMAGE:4994

Dip2a DIP2 disco-interacting protein 2 homolog A (Drosophila) ( MGI:2385920)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:4994
Fig3Bii. from [doi:10.1016/S0378-1119(02)00694-7] Gene 293: 59-65, Mukhopadhyay M; Pelka P; DeSousa D; Kablar B; Schindler A; Rudnicki MA; Campos AR, Cloning, genomic organization and expression pattern of a novel Drosophila gene, the disco-interacting protein 2 (dip2), and its murine homolog. Copyright 2002 [PMID:12137943]

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:4994Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4994_wholemount_moderate.wlz
4994_wholemount_weak.wlz
4994_wholemount_notDetected.wlz
4994_wholemount_strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4994_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
telencephalon
strong strong
regionalExpression is deteted in the telencephalic vesicle. The strongest expression of mDip2 was observed in the neocortex and striatum of the telencephalon.
mesencephalic vesicle
detected detected
hindbrain
detected detected
gradedExpression is detected in the rhombencephalic vesicle. Mesencephalic and rhombencephalic distribution of mDip2 transcripts were in a gradient fashion, slowly disappearing caudally towards the spinal cord.
eye
detected detected
regionalExpression is detected in the optic vesicle.
ear
detected detected
regionalExpression is detected in the otic vesicle.
future spinal cord
not detected not detected
homogeneous
diencephalon
strong strong
regionalThe strongest expression of mDip2 was observed in the neocortex and striatum of the telencephalon, as well as in the thalamic regions of the diencephalon.
midbrain
detected detected
gradedMesencephalic and rhombencephalic distribution of mDip2 transcripts were in a gradient fashion, slowly disappearing caudally towards the spinal cord.
brain
detected detected
regionalThe expression of mDip2 was clearly absent in two narrow brain regions: the border between the telencephalon and the diencephalon, as well as at the border between the mesencephalon and the rhombencephalon.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Dip2a probeA
Entity Detected:Dip2a, DIP2 disco-interacting protein 2 homolog A (Drosophila) ( MGI:2385920)
Notes:The Dip2a (Dip2) probe used in this study by Mukhopadhyay et al., 2002 [PMID:12137943] is described as a "Dig-labeled probe generated from a 400 bp fragment of the mouse cDNA corresponding to the C-terminus of the predicted protein."
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Staining procedure:alkaline phosphatase + NBT/BCIP
General Information
Authors:Mukhopadhyay M; Pelka P; DeSousa D; Kablar B; Schindler A; Rudnicki MA; Campos AR, 2002 [PMID:12137943] , Indexed and Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S0378-1119(02)00694-7] [ PMID:12137943] Mukhopadhyay M, Pelka P, DeSousa D, Kablar B, Schindler A, Rudnicki MA, Campos AR 2002 Cloning, genomic organization and expression pattern of a novel Drosophila gene, the disco-interacting protein 2 (dip2), and its murine homolog. Gene (293):59-65
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE