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EMAGE:4999

Dkk4 dickkopf homolog 4 (Xenopus laevis) ( MGI:2385299)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:4999
Fig2A. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.ydbio.2007.02.035] Dev Biol 305(2): 498-507, Bazzi H; Fantauzzo KA; Richardson GD; Jahoda CA; Christiano AM, The Wnt inhibitor, Dickkopf 4, is induced by canonical Wnt signaling during ectodermal appendage morphogenesis. Copyright 2007 [PMID:17397822]

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: presumptive dental (molar field) pre-placodes (arrows on maxilla, upper, and mandible, lower); asterisk indicates the developing eye.
Expression Pattern Description
Spatial Annotation:
EMAGE:4999Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4999_wholemount_moderate_3D_1.wlz
4999_wholemount_notDetected_3D_1.wlz
4999_wholemount_strong_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4999_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
1st branchial arch maxillary component
detected detected
regionalDkk4 mRNA is evident at the presumptive sites of molar development in the maxilla and mandible.
1st branchial arch mandibular component
detected detected
regionalDkk4 mRNA is evident at the presumptive sites of molar development in the maxilla and mandible.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Dkk4 probeA
Entity Detected:Dkk4, dickkopf homolog 4 (Xenopus laevis) ( MGI:2385299)
Notes:The Dkk4 used in this study by Bazzi et al., 2007 [PMID:17397822] is described as being "amplified by PCR from an E14 embryo cDNA stock. A full length Dkk4 cDNA was used as a template for the probe."
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Bazzi H; Fantauzzo KA; Richardson GD; Jahoda CA; Christiano AM, 2007 [PMID:17397822] , Indexed and Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/j.ydbio.2007.02.035] [ PMID:17397822] Bazzi H, Fantauzzo KA, Richardson GD, Jahoda CA, Christiano AM 2007 The Wnt inhibitor, Dickkopf 4, is induced by canonical Wnt signaling during ectodermal appendage morphogenesis. Dev Biol (305):498-507
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE