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EMAGE:5032

Sema4a sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A ( MGI:107560)
TS18 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:5032 EMAGE:5032 EMAGE:5032
Fig 1A. [doi:10.1038/sj.emboj.7601589] Toyofuku T; Yabuki M; Kamei J; Kamei M; Makino N; Kumanogoh A; Hori M. EMBO J 2007 Mar 7;26(5):1373-84. "Semaphorin-4A, an activator for T-cell-mediated immunity, suppresses angiogenesis via Plexin-D1." [PMID:17318185] © Nature Publishing Group. Reproduced with permission from EMBO J. Fig 1B. [doi:10.1038/sj.emboj.7601589] Toyofuku T; Yabuki M; Kamei J; Kamei M; Makino N; Kumanogoh A; Hori M. EMBO J 2007 Mar 7;26(5):1373-84. "Semaphorin-4A, an activator for T-cell-mediated immunity, suppresses angiogenesis via Plexin-D1." [PMID:17318185] © Nature Publishing Group. Reproduced with permission from EMBO J. Fig 1C. [doi:10.1038/sj.emboj.7601589] Toyofuku T; Yabuki M; Kamei J; Kamei M; Makino N; Kumanogoh A; Hori M. EMBO J 2007 Mar 7;26(5):1373-84. "Semaphorin-4A, an activator for T-cell-mediated immunity, suppresses angiogenesis via Plexin-D1." [PMID:17318185] © Nature Publishing Group. Reproduced with permission from EMBO J.

Expression pattern clarity: one star
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
(A) Whole-mount in situ hybridization of an E10.5 mouse embryo shows Sema4A expression. The magnified views of the embryo reveal Sema4A mRNA expression within the cardiac ventricle (B, arrowhead) and the dorsal ends of intersomitic blood vessels (C, arrows).
Expression Pattern Description
Spatial Annotation:
EMAGE:5032Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5032_wholemount__possible.wlz
5032_wholemount__notDetected.wlz
5032_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5032_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
primitive ventricle
detected detected
cardiovascular system
detected detected
regionalExpression was detected in the dorsal ends of intersomitic blood vessels.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:3763059
Entity Detected:Sema4a, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A ( MGI:107560)
Notes:The Sema4a probe used in this study by Toyofuku et al., 2007 [PMID:17318185] is of unreported sequence.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS18
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Toyofuku T; Yabuki M; Kamei J; Kamei M; Makino N; Kumanogoh A; Hori M, 2007 [PMID:17318185] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1038/sj.emboj.7601589] [ PMID:17318185] Toyofuku T, Yabuki M, Kamei J, Kamei M, Makino N, Kumanogoh A, Hori M 2007 Semaphorin-4A, an activator for T-cell-mediated immunity, suppresses angiogenesis via Plexin-D1. EMBO J (26):1373-84
Links:MGI:3763061 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI