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EMAGE:5058

Smad5 MAD homolog 5 (Drosophila) ( MGI:1328787)
TS14 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:5058
Figure 2E. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.ydbio.2006.04.442] Dev Biol 296: 104-18, Arnold SJ; Maretto S; Islam A; Bikoff EK; Robertson EJ, "Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo." Copyright 2006 [PMID:16765933]

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:5058Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5058_wholemount_moderate_3D_1.wlz
5058_wholemount_possible_3D_1.wlz
5058_wholemount_notDetected_3D_1.wlz
5058_wholemount_strong_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5058_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
embryo
detected detected
Broadly expressed throughout the embryo proper.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:36140
Entity Detected:Smad5, MAD homolog 5 (Drosophila) ( MGI:1328787)
Notes:The Smad1 probe used in this study by Arnold et al., 2006 [PMID:16765933] is indicated as that originally described by Meersseman et al., 1997 [PMID:9076683] i.e. "full-size MusMLP (Smad5)".
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS14
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Arnold SJ; Maretto S; Islam A; Bikoff EK; Robertson EJ, 2006 [PMID:16765933] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/j.ydbio.2006.04.442] [ PMID:16765933] Arnold SJ, Maretto S, Islam A, Bikoff EK, Robertson EJ 2006 Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo. Dev Biol (296):104-18
 [ doi:10.1016/S0925-4773(96)00629-6] [ PMID:9076683] Meersseman G, Verschueren K, Nelles L, Blumenstock C, Kraft H, Wuytens G, Remacle J, Kozak CA, Tylzanowski P, Niehrs C, Huylebroeck D 1997 The C-terminal domain of Mad-like signal transducers is sufficient for biological activity in the Xenopus embryo and transcriptional activation. Mech Dev (61):127-40
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE